Basic Information
ID: ALA1029069
Type: Functional
Description: Inhibition of Hedgehog signaling pathway in mouse TM3 cells bearing pTA-8xGli-Luc reporter construct assessed as transcriptional modulation of Gli after 48 hrs by luciferase assay
Organism: Mus musculus
Cell type: TM3
Activity Charts
Bioactivity
Activity Types for Assay ALA1029069
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 468.48 | 5.76 | 5.76 |
| 468.48 | 5.76 | 5.76 |
| 501.55 | 6.59 | 6.59 |
| 501.55 | 6.59 | 6.59 |
| 411.63 | 5.00 | 5.00 |
| 468.48 | 5.76 | 5.76 |
| 514.55 | 6.83 | 6.83 |
| 550.60 | 6.38 | 6.38 |
| 500.56 | 7.19 | 7.19 |
| 501.55 | 6.59 | 6.59 |
| 507.58 | 6.65 | 6.65 |
| 507.58 | 6.65 | 6.65 |
| 501.55 | 6.59 | 6.59 |
| 517.55 | 6.29 | 6.29 |
| 487.53 | 6.28 | 6.28 |
| 453.97 | 5.91 | 5.91 |
| 419.53 | 5.26 | 5.26 |
| 500.56 | 7.19 | 7.19 |
| 501.55 | 6.59 | 6.59 |
| 530.59 | 7.20 | 7.20 |
| 557.62 | 7.15 | 7.15 |
| 514.59 | 7.75 | 7.75 |
| 568.56 | 8.29 | 8.29 |
| 551.61 | 7.74 | 7.74 |
| 486.54 | 7.51 | 7.51 |
| 506.59 | 7.25 | 7.25 |
| 490.53 | 6.78 | 6.78 |
| 521.61 | 6.96 | 6.96 |
| 521.61 | 6.96 | 6.96 |
| 504.55 | 7.09 | 7.09 |
| 494.56 | 6.03 | 6.03 |