Basic Information
ID: ALA1035217
Type: Binding
Description: Inhibition of TACE in mouse Raw264.7 cells assessed as inhibition of LPS-induced TNFalpha production treated 1 hr before LPS challenge measured 4 hrs post LPS challenge
Format: BAO_0000219
Organism: Mus musculus
Cell type: RAW264.7
Target: ADAM17(ALA4379)
Document: ALA1137760
Inhibition of TACE in mouse Raw264.7 cells assessed as inhibition of LPS-induced TNFalpha production treated 1 hr before LPS challenge measured 4 hrs post LPS challenge: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1035217
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 532.62 | 4.07 | 4.07 |
| 426.49 | 2.85 | 2.85 |
| 442.49 | 2.55 | 2.55 |