Basic Information
ID: ALA1035280
Type: Binding
Description: Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level at 50 uM after 4 hrs by G-LISA relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1035280
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 421.59 | 4.89 | 4.89 |
| 440.53 | 2.67 | 2.67 |
| 411.55 | 3.07 | 3.07 |
| 414.49 | 3.00 | 3.00 |
| 423.86 | 3.02 | 3.02 |
| 360.42 | 2.63 | 2.63 |
| 356.47 | 3.36 | 3.36 |
| 419.50 | 3.50 | 3.50 |
| 376.44 | 3.15 | 3.15 |
| 416.51 | 4.39 | 4.39 |
| 368.52 | 3.05 | 3.05 |
| 371.48 | 2.83 | 2.83 |
| 403.55 | 4.92 | 4.92 |
| 410.50 | 3.28 | 3.28 |
| 378.43 | 1.94 | 1.94 |
| 419.44 | 2.98 | 2.98 |
| 362.45 | 2.62 | 2.62 |
| 402.52 | 3.10 | 3.10 |
| 377.47 | 4.20 | 4.20 |
| 340.38 | 3.03 | 3.03 |
| 404.49 | 2.23 | 2.23 |
| 405.46 | 2.01 | 2.01 |
| 384.52 | 3.07 | 3.07 |
| 428.53 | 2.22 | 2.22 |
| 410.54 | 3.44 | 3.44 |
| 377.43 | 3.99 | 3.99 |
| 410.60 | 4.18 | 4.18 |
| 403.44 | 3.26 | 3.26 |
| 396.45 | 4.08 | 4.08 |
| 363.44 | 4.14 | 4.14 |
| 400.46 | 1.79 | 1.79 |
| 388.49 | 3.06 | 3.06 |
| 354.49 | 2.66 | 2.66 |
| 425.47 | 2.61 | 2.61 |
| 400.43 | 3.37 | 3.37 |
| 422.55 | 2.61 | 2.61 |
| 420.47 | 3.57 | 3.57 |
| 390.45 | 2.39 | 2.39 |
| 411.50 | 3.80 | 3.80 |
| 384.52 | 3.07 | 3.07 |
| 415.56 | 3.78 | 3.78 |
| 414.48 | 3.83 | 3.83 |
| 374.37 | 2.62 | 2.62 |
| 380.47 | 4.47 | 4.47 |
| 368.43 | 2.38 | 2.38 |
| 371.48 | 3.08 | 3.08 |
| 385.50 | 3.14 | 3.14 |
| 379.38 | 3.97 | 3.97 |
| 372.40 | 3.77 | 3.77 |
| 412.52 | 2.72 | 2.72 |
| 437.97 | 2.92 | 2.92 |