Inhibition of mPGES1 in IL1-beta treated human A549 cell microsomal membrane assessed as blockade of PGH2 to PGE2 conversion after 1 min

Basic Information

ID: ALA1036472

Type: Binding

Description: Inhibition of mPGES1 in IL1-beta treated human A549 cell microsomal membrane assessed as blockade of PGH2 to PGE2 conversion after 1 min

Format: BAO_0000251

Organism: Homo sapiens

Cell type: A549

Subcellular Fraction: Microsome

Target: Prostaglandin E synthase(ALA5658)

Document: ALA1158497

Inhibition of mPGES1 in IL1-beta treated human A549 cell microsomal membrane assessed as blockade of PGH2 to PGE2 conversion after 1 min: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA1036472

IC50

Total(1)

Parent Molecular Weight	ALogP	Polar Surface Area
379.89	5.68	5.68

Parent Molecular Weight

ALogP

Polar Surface Area

379.89

5.68

Inhibition of mPGES1 in IL1-beta treated human A549 cell microsomal membrane assessed as blockade of PGH2 to PGE2 conversion after 1 min

Basic Information

Activity Charts

Compound Summary