Basic Information
ID: ALA1036605
Type: Binding
Description: Inhibition of rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of glutamate and glycine-induced evoked current by two electrode voltage clamp method
Organism: Rattus norvegicus
Cell type: Oocyte
Activity Charts
Bioactivity
Activity Types for Assay ALA1036605
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 325.45 | 3.77 | 3.77 |
| 433.36 | 2.94 | 2.94 |
| 451.35 | 3.08 | 3.08 |
| 451.35 | 3.08 | 3.08 |
| 447.38 | 3.25 | 3.25 |
| 433.36 | 2.94 | 2.94 |
| 568.48 | 4.76 | 4.76 |
| 581.52 | 4.77 | 4.77 |
| 524.47 | 4.24 | 4.24 |
| 524.47 | 4.24 | 4.24 |
| 495.43 | 4.37 | 4.37 |
| 530.50 | 4.31 | 4.31 |
| 447.38 | 3.33 | 3.33 |
| 461.41 | 3.72 | 3.72 |
| 475.44 | 4.11 | 4.11 |
| 397.30 | 3.52 | 3.52 |
| 466.19 | 4.31 | 4.31 |
| 537.51 | 4.89 | 4.89 |
| 553.51 | 4.60 | 4.60 |
| 433.36 | 2.94 | 2.94 |
| 447.38 | 3.28 | 3.28 |
| 500.64 | 4.87 | 4.87 |
| 447.38 | 2.96 | 2.96 |
| 385.25 | 3.47 | 3.47 |
| 433.36 | 2.94 | 2.94 |
| 398.91 | 2.28 | 2.28 |
| 477.41 | 2.64 | 2.64 |
| 489.47 | 4.45 | 4.45 |
| 539.48 | 4.56 | 4.56 |
| 539.48 | 4.56 | 4.56 |
| 398.91 | 2.28 | 2.28 |
| 398.91 | 2.28 | 2.28 |
| 433.36 | 2.94 | 2.94 |
| 416.90 | 2.42 | 2.42 |
| 416.90 | 2.42 | 2.42 |
| 382.46 | 1.77 | 1.77 |
| 382.46 | 1.77 | 1.77 |
| 382.46 | 1.77 | 1.77 |
| 400.45 | 1.91 | 1.91 |
| 380.47 | 1.34 | 1.34 |
| 380.47 | 1.34 | 1.34 |
| 380.47 | 1.34 | 1.34 |
| 396.47 | 1.04 | 1.04 |
| 396.47 | 1.04 | 1.04 |
| 408.48 | 1.36 | 1.36 |
| 392.52 | 2.25 | 2.25 |
| 414.53 | 3.30 | 3.30 |
| 409.46 | 1.54 | 1.54 |
| 447.38 | 3.28 | 3.28 |
| 461.41 | 3.67 | 3.67 |
| 477.41 | 2.64 | 2.64 |
| 475.44 | 4.06 | 4.06 |
| 489.47 | 4.45 | 4.45 |
| 503.49 | 4.84 | 4.84 |
| 489.47 | 4.31 | 4.31 |
| 529.53 | 5.23 | 5.23 |
| 475.44 | 4.06 | 4.06 |
| 523.48 | 4.85 | 4.85 |
| 539.48 | 4.56 | 4.56 |
| 539.48 | 4.56 | 4.56 |
| 539.48 | 4.56 | 4.56 |
| 555.48 | 4.26 | 4.26 |
| 555.48 | 4.26 | 4.26 |
| 553.51 | 4.86 | 4.86 |
| 583.53 | 4.87 | 4.87 |
| 583.53 | 4.87 | 4.87 |
| 567.49 | 4.58 | 4.58 |
| 557.93 | 5.50 | 5.50 |
| 602.38 | 5.61 | 5.61 |
| 541.47 | 4.99 | 4.99 |
| 541.47 | 4.99 | 4.99 |
| 541.47 | 4.99 | 4.99 |
| 559.46 | 5.13 | 5.13 |
| 577.45 | 5.27 | 5.27 |
| 613.43 | 5.55 | 5.55 |
| 537.51 | 5.16 | 5.16 |
| 537.51 | 5.16 | 5.16 |
| 591.48 | 5.87 | 5.87 |