Basic Information
ID: ALA1037217
Type: Functional
Description: Allosteric modulation of rat NK2 receptor expressed in HEK293 cells assessed as formation of active receptor calcium-triggering conformation at 10 uM in presence of 20nM NKA-Bo by FRET assay
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: HEK293
Target: Neurokinin 2 receptor(ALA4554)
Document: ALA1156054
Allosteric modulation of rat NK2 receptor expressed in HEK293 cells assessed as formation of active receptor calcium-triggering conformation at 10 uM in presence of 20nM NKA-Bo by FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1037217
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 449.60 | 5.19 | 5.19 |
| 324.43 | 5.44 | 5.44 |
| 270.76 | 3.87 | 3.87 |
| 270.76 | 3.87 | 3.87 |
| 347.46 | 5.10 | 5.10 |
| 324.43 | 5.44 | 5.44 |
| 325.42 | 4.84 | 4.84 |
| 349.43 | 3.38 | 3.38 |
| 360.50 | 4.76 | 4.76 |
| 286.38 | 4.37 | 4.37 |
| 365.27 | 5.13 | 5.13 |
| 529.81 | 9.87 | 9.87 |
| 365.27 | 5.13 | 5.13 |
| 412.27 | 4.97 | 4.97 |
| 390.53 | 6.15 | 6.15 |
| 316.40 | 4.37 | 4.37 |
| 287.37 | 3.76 | 3.76 |
| 287.37 | 3.76 | 3.76 |
| 262.36 | 3.73 | 3.73 |
| 266.34 | 3.22 | 3.22 |
| 409.53 | 5.63 | 5.63 |
| 304.31 | 4.23 | 4.23 |
| 285.39 | 4.48 | 4.48 |
| 314.43 | 5.15 | 5.15 |
| 418.54 | 3.72 | 3.72 |
| 333.43 | 4.41 | 4.41 |
| 305.38 | 3.93 | 3.93 |
| 372.51 | 4.85 | 4.85 |
| 387.53 | 3.62 | 3.62 |
| 375.51 | 5.58 | 5.58 |