Basic Information
ID: ALA1037719
Type: Functional
Description: Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-induced adenylyl cyclase activity
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA1037719
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 527.59 | 5.70 | 5.70 |
| 463.50 | 4.16 | 4.16 |
| 463.93 | 4.61 | 4.61 |
| 491.56 | 5.30 | 5.30 |
| 437.46 | 4.09 | 4.09 |
| 449.47 | 4.04 | 4.04 |
| 449.47 | 4.12 | 4.12 |
| 505.58 | 5.55 | 5.55 |
| 407.82 | 3.11 | 3.11 |
| 477.53 | 4.91 | 4.91 |
| 469.53 | 4.22 | 4.22 |
| 393.43 | 3.00 | 3.00 |
| 393.43 | 3.00 | 3.00 |
| 379.41 | 2.51 | 2.51 |
| 505.58 | 5.63 | 5.63 |
| 539.60 | 5.75 | 5.75 |
| 539.60 | 5.82 | 5.82 |
| 477.53 | 4.99 | 4.99 |
| 407.82 | 3.11 | 3.11 |
| 469.53 | 4.22 | 4.22 |
| 437.46 | 4.09 | 4.09 |
| 463.50 | 4.60 | 4.60 |
| 403.40 | 2.46 | 2.46 |
| 479.54 | 5.11 | 5.11 |
| 423.44 | 3.61 | 3.61 |
| 513.56 | 5.31 | 5.31 |
| 491.56 | 5.38 | 5.38 |
| 511.97 | 5.20 | 5.20 |
| 451.49 | 4.48 | 4.48 |
| 497.48 | 4.98 | 4.98 |
| 391.37 | 2.59 | 2.59 |
| 495.52 | 4.69 | 4.69 |
| 553.63 | 6.14 | 6.14 |
| 511.97 | 5.20 | 5.20 |
| 451.49 | 4.48 | 4.48 |
| 498.37 | 5.27 | 5.27 |
| 465.52 | 4.87 | 4.87 |
| 441.37 | 3.47 | 3.47 |
| 527.59 | 5.70 | 5.70 |
| 421.49 | 3.78 | 3.78 |
| 421.49 | 3.78 | 3.78 |
| 442.27 | 3.76 | 3.76 |
| 423.82 | 2.94 | 2.94 |
| 527.97 | 5.04 | 5.04 |
| 463.93 | 4.61 | 4.61 |
| 546.42 | 5.85 | 5.85 |
| 553.63 | 6.22 | 6.22 |
| 423.44 | 3.61 | 3.61 |
| 497.95 | 4.81 | 4.81 |
| 379.41 | 2.51 | 2.51 |
| 447.47 | 4.10 | 4.10 |