Basic Information
ID: ALA1037785
Type: Functional
Description: Fold resistance, ratio of EC50 for indinavir-resistant HIV1 harboring L10R/M46I/L63P/V82T/I84V mutant protease infected in human MT4 cells to EC50 for HIV1 pNL4-3 infected in human MT4 cells
Format: BAO_0000218
Organism: Human immunodeficiency virus 1
Cell type: MT4
Target: Human immunodeficiency virus 1(ALA378)
Document: ALA1154734
Fold resistance, ratio of EC50 for indinavir-resistant HIV1 harboring L10R/M46I/L63P/V82T/I84V mutant protease infected in human MT4 cells to EC50 for HIV1 pNL4-3 infected in human MT4 cells: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1037785
Ratio EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 628.81 | 4.33 | 4.33 |
| 575.73 | 3.71 | 3.71 |
| 646.81 | 2.81 | 2.81 |
| 539.70 | 3.14 | 3.14 |
| 614.14 | 4.19 | 4.19 |
| 591.73 | 3.41 | 3.41 |
| 570.76 | 2.95 | 2.95 |
| 511.64 | 2.38 | 2.38 |
| 509.63 | 1.83 | 1.83 |
| 618.80 | 3.66 | 3.66 |
| 632.83 | 3.97 | 3.97 |
| 630.81 | 3.84 | 3.84 |
| 582.77 | 3.09 | 3.09 |
| 554.71 | 2.34 | 2.34 |
| 553.73 | 3.53 | 3.53 |