Basic Information
ID: ALA1037933
Type: Binding
Description: Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISA
Organism: Homo sapiens
Cell type: IMR-32
Activity Charts
Bioactivity
Activity Types for Assay ALA1037933
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 430.94 | 1.39 | 1.39 |
| 442.95 | 1.53 | 1.53 |
| 337.83 | 2.90 | 2.90 |
| 362.84 | 2.65 | 2.65 |
| 387.84 | 3.39 | 3.39 |
| 361.85 | 2.76 | 2.76 |
| 438.94 | 2.97 | 2.97 |
| 375.88 | 3.15 | 3.15 |
| 396.86 | 1.80 | 1.80 |
| 410.88 | 2.19 | 2.19 |
| 339.80 | 1.75 | 1.75 |
| 409.90 | 2.69 | 2.69 |
| 367.86 | 2.12 | 2.12 |
| 424.91 | 2.58 | 2.58 |
| 376.27 | 1.75 | 1.75 |
| 355.87 | 2.47 | 2.47 |
| 440.91 | 1.82 | 1.82 |
| 381.84 | 2.21 | 2.21 |
| 381.89 | 2.78 | 2.78 |
| 395.91 | 3.17 | 3.17 |
| 407.92 | 3.31 | 3.31 |
| 398.32 | 3.88 | 3.88 |
| 398.32 | 3.88 | 3.88 |
| 380.86 | 1.58 | 1.58 |
| 394.88 | 1.97 | 1.97 |
| 409.90 | 1.72 | 1.72 |
| 431.87 | 4.25 | 4.25 |
| 431.87 | 4.25 | 4.25 |
| 338.82 | 1.32 | 1.32 |
| 416.91 | 1.00 | 1.00 |