Basic Information
ID: ALA1038283
Type: Functional
Description: Antagonist activity at human mGluR1 receptor expressed in CHO cell membranes assessed as inhibition of L-glutamate-induced calcium mobilization by FLIPR
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Metabotropic glutamate receptor 1(ALA3772)
Document: ALA1155999
Antagonist activity at human mGluR1 receptor expressed in CHO cell membranes assessed as inhibition of L-glutamate-induced calcium mobilization by FLIPR: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1038283
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 358.42 | 2.66 | 2.66 |
| 307.38 | 3.56 | 3.56 |
| 322.37 | 3.20 | 3.20 |
| 322.37 | 3.20 | 3.20 |
| 321.38 | 2.78 | 2.78 |
| 278.31 | 2.84 | 2.84 |
| 292.34 | 3.23 | 3.23 |
| 335.41 | 3.12 | 3.12 |
| 333.40 | 2.87 | 2.87 |
| 304.35 | 3.23 | 3.23 |
| 290.33 | 2.77 | 2.77 |
| 337.36 | 2.75 | 2.75 |
| 351.38 | 3.14 | 3.14 |
| 340.39 | 3.87 | 3.87 |
| 318.38 | 3.40 | 3.40 |
| 330.39 | 3.40 | 3.40 |
| 351.39 | 3.14 | 3.14 |
| 275.31 | 3.12 | 3.12 |
| 287.33 | 3.19 | 3.19 |
| 349.37 | 2.90 | 2.90 |
| 286.34 | 3.79 | 3.79 |