Basic Information
ID: ALA1038284
Type: Functional
Description: Antagonist activity at human mGluR5 receptor expressed in CHO cell membranes assessed as inhibition of L-glutamate-induced calcium mobilization by FLIPR
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Metabotropic glutamate receptor 5(ALA3227)
Document: ALA1155999
Antagonist activity at human mGluR5 receptor expressed in CHO cell membranes assessed as inhibition of L-glutamate-induced calcium mobilization by FLIPR: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1038284
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 358.42 | 2.66 | 2.66 |
| 337.36 | 2.75 | 2.75 |
| 351.38 | 3.14 | 3.14 |
| 351.39 | 3.14 | 3.14 |
| 349.37 | 2.90 | 2.90 |