Inhibition of topoisomerase 2 from mouse P388 cells assessed as relaxation of pBR322 DNA by agarose gel electrophoresis relative to etoposide

Basic Information

ID: ALA1039759

Type: Binding

Description: Inhibition of topoisomerase 2 from mouse P388 cells assessed as relaxation of pBR322 DNA by agarose gel electrophoresis relative to etoposide

Format: BAO_0000219

Organism: Mus musculus

Cell type: P388

Target:  DNA topoisomerase II alpha(ALA3586)

Document:  ALA1152689

Inhibition of topoisomerase 2 from mouse P388 cells assessed as relaxation of pBR322 DNA by agarose gel electrophoresis relative to etoposide: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
294.353.683.68
278.363.983.98
278.363.983.98
264.333.673.67
298.774.334.33
309.333.583.58
309.333.583.58
306.373.883.88