Basic Information
ID: ALA1040363
Type: Binding
Description: Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester after 24 hrs
Format: BAO_0000219
Organism: Rattus norvegicus
Target: Acyl coenzyme A:cholesterol acyltransferase 1(ALA285)
Document: ALA1154055
Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester after 24 hrs: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1040363
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 501.73 | 7.29 | 7.29 |
| 499.70 | 7.30 | 7.30 |
| 617.66 | 6.89 | 6.89 |
| 671.63 | 7.78 | 7.78 |
| 685.66 | 7.83 | 7.83 |
| 544.74 | 6.89 | 6.89 |
| 514.71 | 6.88 | 6.88 |
| 585.75 | 7.10 | 7.10 |
| 586.82 | 8.06 | 8.06 |
| 624.27 | 6.61 | 6.61 |
| 652.32 | 7.21 | 7.21 |
| 514.71 | 6.88 | 6.88 |
| 515.70 | 6.28 | 6.28 |
| 544.74 | 6.89 | 6.89 |
| 588.62 | 6.28 | 6.28 |
| 603.64 | 6.59 | 6.59 |
| 588.62 | 6.28 | 6.28 |
| 662.70 | 6.04 | 6.04 |
| 645.72 | 7.67 | 7.67 |
| 647.69 | 6.26 | 6.26 |
| 661.72 | 6.65 | 6.65 |
| 618.65 | 6.29 | 6.29 |
| 661.72 | 6.65 | 6.65 |