Assay Report Card

Basic Information

ID: ALA1040421

Type: Functional

Description: Antagonist activity at mouse P2Y2 receptor expressed in NG108-15 hybrid cells assessed as inhibition of 1 uM UTP-induced intracellular calcium release preincubated 30 mins before UTP challenge by fluorescence assay

Organism: Mus musculus

Cell type: NG108-15

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
484.14-2.50-2.50
266.15-1.38-1.38
280.17-0.99-0.99
394.11-0.66-0.66
408.13-0.27-0.27
422.160.120.12
342.180.000.00
236.12-1.35-1.35
264.17-0.57-0.57
278.20-0.18-0.18
396.08-1.12-1.12
438.160.050.05
426.10-1.15-1.15
440.13-0.76-0.76