Basic Information
ID: ALA1041649
Type: Functional
Description: Antagonist activity at rat recombinant NR1/NR2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current at 3 uM by two electrode voltage clamp method relative to control
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: Oocyte
Target: Glutamate NMDA receptor; Grin1/Grin2a(ALA2096680)
Document: ALA1152519
Antagonist activity at rat recombinant NR1/NR2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current at 3 uM by two electrode voltage clamp method relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1041649
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 431.34 | 3.49 | 3.49 |
| 433.31 | 2.94 | 2.94 |
| 429.37 | 4.05 | 4.05 |
| 416.37 | 4.00 | 4.00 |
| 432.33 | 2.97 | 2.97 |
| 442.37 | 4.24 | 4.24 |
| 449.38 | 3.65 | 3.65 |
| 461.40 | 3.32 | 3.32 |
| 444.34 | 3.69 | 3.69 |
| 432.33 | 2.97 | 2.97 |
| 429.33 | 3.57 | 3.57 |
| 446.36 | 3.36 | 3.36 |
| 446.36 | 2.27 | 2.27 |
| 445.33 | 3.15 | 3.15 |
| 430.36 | 3.16 | 3.16 |
| 444.38 | 3.92 | 3.92 |
| 430.31 | 2.76 | 2.76 |
| 456.31 | 2.62 | 2.62 |
| 430.36 | 3.53 | 3.53 |
| 418.35 | 3.45 | 3.45 |
| 458.37 | 3.09 | 3.09 |
| 456.40 | 3.65 | 3.65 |
| 427.35 | 4.13 | 4.13 |