Basic Information
ID: ALA1041789
Type: Functional
Description: Agonist activity at TGR5 expressed in CHO cells by CRE-driven luciferase reporter gene assay relative to litocholic acid
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA1041789
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.71 | 7.09 | 7.09 |
| 513.76 | 6.21 | 6.21 |
| 442.73 | 7.00 | 7.00 |
| 454.70 | 7.30 | 7.30 |
| 469.71 | 7.56 | 7.56 |
| 470.74 | 7.18 | 7.18 |
| 458.68 | 6.10 | 6.10 |
| 456.71 | 7.23 | 7.23 |
| 458.73 | 7.17 | 7.17 |
| 456.71 | 7.09 | 7.09 |
| 376.58 | 5.51 | 5.51 |
| 442.73 | 7.00 | 7.00 |
| 488.71 | 5.03 | 5.03 |
| 426.73 | 8.46 | 8.46 |
| 424.71 | 8.23 | 8.23 |
| 426.73 | 8.02 | 8.02 |
| 488.71 | 5.18 | 5.18 |
| 556.78 | 7.51 | 7.51 |
| 456.67 | 6.02 | 6.02 |
| 454.70 | 7.75 | 7.75 |
| 538.81 | 8.61 | 8.61 |
| 526.80 | 8.30 | 8.30 |
| 485.75 | 6.46 | 6.46 |
| 495.79 | 7.28 | 7.28 |
| 472.71 | 6.30 | 6.30 |
| 511.75 | 7.65 | 7.65 |
| 573.82 | 8.94 | 8.94 |
| 551.81 | 8.59 | 8.59 |
| 525.77 | 8.04 | 8.04 |
| 553.83 | 8.67 | 8.67 |
| 455.73 | 6.49 | 6.49 |
| 512.78 | 5.61 | 5.61 |
| 543.83 | 6.13 | 6.13 |
| 529.81 | 5.47 | 5.47 |
| 527.79 | 5.53 | 5.53 |
| 470.74 | 7.74 | 7.74 |
| 546.84 | 8.75 | 8.75 |
| 560.86 | 9.40 | 9.40 |
| 498.75 | 7.47 | 7.47 |
| 496.78 | 8.04 | 8.04 |
| 496.78 | 8.04 | 8.04 |
| 510.80 | 8.43 | 8.43 |
| 510.80 | 8.43 | 8.43 |
| 615.86 | 7.80 | 7.80 |
| 585.87 | 8.03 | 8.03 |
| 533.80 | 8.01 | 8.01 |
| 453.71 | 7.09 | 7.09 |
| 510.81 | 7.22 | 7.22 |
| 514.80 | 6.05 | 6.05 |
| 542.85 | 6.83 | 6.83 |
| 544.82 | 5.41 | 5.41 |
| 558.85 | 6.07 | 6.07 |
| 474.73 | 6.14 | 6.14 |
| 499.78 | 6.11 | 6.11 |
| 541.86 | 7.28 | 7.28 |
| 541.82 | 6.68 | 6.68 |