Basic Information
ID: ALA1044822
Type: Binding
Description: Inhibition of human DHFR assessed as rate of NADPH consumption using dihydrofolate as substrate
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1044822
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.32 | 1.26 | 1.26 |
| 314.35 | 1.26 | 1.26 |
| 328.37 | 1.57 | 1.57 |
| 328.37 | 1.82 | 1.82 |
| 342.40 | 2.13 | 2.13 |
| 330.34 | 0.75 | 0.75 |
| 344.37 | 1.06 | 1.06 |
| 344.37 | 1.41 | 1.41 |
| 358.40 | 1.71 | 1.71 |
| 358.45 | 3.78 | 3.78 |
| 372.47 | 4.09 | 4.09 |
| 386.50 | 4.40 | 4.40 |
| 442.61 | 6.03 | 6.03 |
| 358.45 | 3.78 | 3.78 |
| 372.47 | 4.09 | 4.09 |
| 386.50 | 4.40 | 4.40 |
| 442.61 | 6.03 | 6.03 |
| 358.45 | 3.78 | 3.78 |
| 358.45 | 3.78 | 3.78 |
| 284.32 | 1.25 | 1.25 |
| 298.35 | 1.56 | 1.56 |
| 312.37 | 1.81 | 1.81 |
| 326.40 | 2.20 | 2.20 |
| 342.40 | 1.82 | 1.82 |
| 356.43 | 2.52 | 2.52 |
| 388.47 | 3.79 | 3.79 |
| 314.35 | 1.05 | 1.05 |
| 328.37 | 1.71 | 1.71 |
| 360.42 | 2.71 | 2.71 |
| 370.45 | 2.77 | 2.77 |
| 372.47 | 3.84 | 3.84 |
| 372.47 | 4.09 | 4.09 |
| 312.37 | 2.12 | 2.12 |
| 386.50 | 4.40 | 4.40 |
| 414.55 | 5.08 | 5.08 |
| 356.43 | 2.38 | 2.38 |