Basic Information
ID: ALA1048319
Type: Binding
Description: Inhibition of mPGES1 expressed in human HeLa cells assessed as inhibition of IL-1-beta/TNF-alpha-induced PGE2 production by Western blot analysis
Organism: Homo sapiens
Cell type: HeLa
Activity Charts
Bioactivity
Activity Types for Assay ALA1048319
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 542.51 | 9.29 | 9.29 |
| 508.06 | 8.64 | 8.64 |
| 556.08 | 8.79 | 8.79 |
| 526.05 | 8.78 | 8.78 |
| 527.04 | 8.17 | 8.17 |
| 544.04 | 8.92 | 8.92 |
| 560.50 | 9.43 | 9.43 |
| 568.09 | 8.98 | 8.98 |
| 540.08 | 9.09 | 9.09 |
| 540.08 | 9.09 | 9.09 |
| 540.08 | 9.09 | 9.09 |
| 375.27 | 6.11 | 6.11 |
| 321.38 | 5.21 | 5.21 |
| 365.26 | 6.65 | 6.65 |
| 376.26 | 5.36 | 5.36 |
| 362.89 | 6.24 | 6.24 |
| 366.37 | 4.55 | 4.55 |
| 373.39 | 4.28 | 4.28 |
| 542.47 | 7.62 | 7.62 |
| 352.44 | 4.63 | 4.63 |
| 484.41 | 5.54 | 5.54 |
| 355.83 | 5.87 | 5.87 |
| 346.39 | 5.09 | 5.09 |
| 445.54 | 4.25 | 4.25 |
| 454.17 | 6.87 | 6.87 |
| 393.26 | 6.24 | 6.24 |
| 528.03 | 7.57 | 7.57 |
| 400.28 | 5.98 | 5.98 |
| 522.58 | 4.65 | 4.65 |
| 496.64 | 8.42 | 8.42 |
| 411.86 | 6.40 | 6.40 |
| 447.39 | 7.89 | 7.89 |
| 339.37 | 5.35 | 5.35 |
| 539.04 | 5.17 | 5.17 |
| 348.81 | 6.14 | 6.14 |
| 330.82 | 6.00 | 6.00 |
| 389.29 | 7.36 | 7.36 |
| 493.61 | 3.93 | 3.93 |
| 403.49 | 6.18 | 6.18 |