Basic Information
ID: ALA1048827
Type: Functional
Description: Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobilization after 1 hr by FLIPR assay
Organism: Rattus norvegicus
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA1048827
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 539.37 | 4.37 | 4.37 |
| 499.61 | 4.94 | 4.94 |
| 513.64 | 5.33 | 5.33 |
| 514.63 | 3.88 | 3.88 |
| 614.74 | 5.45 | 5.45 |
| 660.82 | 4.96 | 4.96 |
| 628.77 | 5.84 | 5.84 |
| 674.85 | 5.35 | 5.35 |
| 507.54 | 4.10 | 4.10 |
| 471.56 | 3.82 | 3.82 |
| 485.58 | 4.38 | 4.38 |
| 542.68 | 4.66 | 4.66 |
| 642.80 | 6.23 | 6.23 |
| 688.87 | 5.74 | 5.74 |
| 688.87 | 5.74 | 5.74 |
| 688.87 | 5.74 | 5.74 |
| 656.82 | 6.62 | 6.62 |
| 620.77 | 4.25 | 4.25 |
| 723.32 | 6.40 | 6.40 |
| 485.58 | 4.38 | 4.38 |
| 584.72 | 3.27 | 3.27 |
| 598.75 | 3.61 | 3.61 |
| 612.77 | 4.00 | 4.00 |
| 626.80 | 4.39 | 4.39 |
| 687.82 | 4.98 | 4.98 |
| 651.76 | 5.43 | 5.43 |
| 700.86 | 5.02 | 5.02 |
| 664.81 | 5.47 | 5.47 |
| 700.86 | 4.72 | 4.72 |
| 624.76 | 2.98 | 2.98 |
| 598.79 | 4.36 | 4.36 |
| 612.82 | 4.75 | 4.75 |
| 499.61 | 4.94 | 4.94 |
| 499.61 | 4.94 | 4.94 |
| 562.74 | 4.81 | 4.81 |
| 548.75 | 5.17 | 5.17 |
| 612.82 | 4.71 | 4.71 |
| 584.76 | 3.97 | 3.97 |
| 598.79 | 4.32 | 4.32 |
| 626.85 | 5.09 | 5.09 |
| 624.83 | 4.85 | 4.85 |
| 638.86 | 5.24 | 5.24 |
| 574.73 | 4.09 | 4.09 |
| 637.78 | 5.79 | 5.79 |
| 582.73 | 3.02 | 3.02 |
| 565.12 | 4.88 | 4.88 |
| 560.70 | 4.23 | 4.23 |
| 418.54 | 3.73 | 3.73 |
| 922.15 | 2.29 | 2.29 |
| 435.57 | 4.27 | 4.27 |