Biodistribution in bone of 1-[4-(6-bromobenzo[1,3]dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta-[c]quinolin-8-yl]ethanone pretreated iv dosed NCr nu...

Basic Information

ID: ALA1049727

Type: ADME

Description: Biodistribution in bone of 1-[4-(6-bromobenzo[1,3]dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta-[c]quinolin-8-yl]ethanone pretreated iv dosed NCr nu/nu mouse xenografted with GPR30 overexpressing human Hec50 cells after 2 hrs

Format: BAO_0000218

Organism: Mus musculus

Strain: NCr nu/nu

Tissue: Bone element

Cell type: Hec50

Target:  Bone(ALA613562)

Document:  ALA1156808

Biodistribution in bone of 1-[4-(6-bromobenzo[1,3]dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta-[c]quinolin-8-yl]ethanone pretreated iv dosed NCr nu/nu mouse xenografted with GPR30 overexpressing human Hec50 cells after 2 hrs: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
656.336.976.97
627.306.846.84