Basic Information
ID: ALA1050554
Type: Binding
Description: Inhibition of mPGES1 in IL-1-beta-stimulated human A549 cells assessed as blockade of PGH2 to PGE2 conversion in presence of 50% fetal bovine serum
Format: BAO_0000219
Organism: Homo sapiens
Cell type: A549
Target: Prostaglandin E synthase(ALA5658)
Document: ALA1156058
Inhibition of mPGES1 in IL-1-beta-stimulated human A549 cells assessed as blockade of PGH2 to PGE2 conversion in presence of 50% fetal bovine serum: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1050554
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 346.79 | 6.33 | 6.33 |
| 378.82 | 5.93 | 5.93 |
| 460.92 | 6.06 | 6.06 |
| 381.24 | 6.98 | 6.98 |
| 461.91 | 6.62 | 6.62 |
| 425.69 | 7.09 | 7.09 |
| 425.69 | 7.09 | 7.09 |
| 486.96 | 6.59 | 6.59 |
| 425.69 | 7.09 | 7.09 |
| 455.71 | 7.10 | 7.10 |
| 487.95 | 6.81 | 6.81 |
| 533.01 | 7.00 | 7.00 |
| 467.73 | 7.29 | 7.29 |
| 591.71 | 8.40 | 8.40 |
| 425.69 | 7.09 | 7.09 |
| 483.77 | 7.32 | 7.32 |
| 374.85 | 6.95 | 6.95 |
| 504.58 | 7.85 | 7.85 |
| 430.87 | 6.73 | 6.73 |
| 446.90 | 5.93 | 5.93 |
| 479.93 | 6.73 | 6.73 |
| 479.93 | 6.73 | 6.73 |
| 467.77 | 8.21 | 8.21 |
| 570.89 | 7.87 | 7.87 |
| 381.24 | 6.98 | 6.98 |
| 436.90 | 6.16 | 6.16 |
| 456.91 | 5.34 | 5.34 |