Basic Information
ID: ALA1050681
Type: Binding
Description: Displacement of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureido)-1H-pyrazol-1-yl)phenylamino)acetamide) from inactive form of p38alpha expressed in Escherichia coli BL21(DE3) cells by enzyme fragment complementation assay
Activity Charts
Bioactivity
Activity Types for Assay ALA1050681
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 281.36 | 3.14 | 3.14 |
| 306.80 | 4.02 | 4.02 |
| 349.44 | 4.40 | 4.40 |
| 297.36 | 3.86 | 3.86 |
| 477.61 | 4.83 | 4.83 |
| 527.67 | 5.99 | 5.99 |
| 464.83 | 5.55 | 5.55 |
| 466.54 | 4.35 | 4.35 |
| 513.01 | 3.98 | 3.98 |
| 383.88 | 5.05 | 5.05 |
| 399.50 | 5.55 | 5.55 |
| 536.60 | 6.72 | 6.72 |
| 506.61 | 6.39 | 6.39 |
| 562.68 | 7.16 | 7.16 |
| 506.61 | 6.39 | 6.39 |
| 505.63 | 7.00 | 7.00 |
| 561.69 | 7.76 | 7.76 |
| 505.63 | 7.00 | 7.00 |
| 535.61 | 7.32 | 7.32 |
| 379.42 | 4.72 | 4.72 |
| 413.87 | 5.38 | 5.38 |
| 490.61 | 7.41 | 7.41 |
| 561.69 | 7.76 | 7.76 |
| 506.61 | 6.39 | 6.39 |
| 429.48 | 5.88 | 5.88 |
| 382.89 | 5.78 | 5.78 |
| 362.48 | 5.43 | 5.43 |
| 505.76 | 7.79 | 7.79 |
| 506.61 | 6.39 | 6.39 |
| 461.57 | 4.64 | 4.64 |