Basic Information
ID: ALA1052812
Type: Functional
Description: Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx at 10 uM by luminescence reporter assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Metabotropic glutamate receptor 6(ALA4573)
Document: ALA1154608
Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx at 10 uM by luminescence reporter assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1052812
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 230.14 | -1.23 | -1.23 |
| 416.13 | 6.45 | 6.45 |
| 161.16 | -0.49 | -0.49 |
| 323.42 | 4.84 | 4.84 |
| 336.29 | 0.75 | 0.75 |
| 299.36 | 4.47 | 4.47 |
| 280.78 | 4.55 | 4.55 |
| 247.32 | 3.09 | 3.09 |
| 275.37 | 3.87 | 3.87 |
| 289.40 | 4.26 | 4.26 |
| 261.35 | 3.48 | 3.48 |
| 214.29 | 3.18 | 3.18 |
| 303.41 | 4.63 | 4.63 |
| 293.39 | 4.54 | 4.54 |
| 317.41 | 4.46 | 4.46 |
| 291.37 | 3.49 | 3.49 |
| 279.34 | 3.62 | 3.62 |
| 295.79 | 4.14 | 4.14 |
| 359.45 | 4.23 | 4.23 |