Basic Information
ID: ALA1052924
Type: Functional
Description: Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production at 10 uM treated 45 mins before forskolin challenge measured after 15 mins by radioimmunoassay relative to NECA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Adenosine A3 receptor(ALA256)
Document: ALA1154768
Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production at 10 uM treated 45 mins before forskolin challenge measured after 15 mins by radioimmunoassay relative to NECA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1052924
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 538.99 | 1.73 | 1.73 |
| 497.72 | 2.61 | 2.61 |
| 450.72 | 2.77 | 2.77 |
| 524.97 | 1.34 | 1.34 |
| 406.87 | 0.86 | 0.86 |
| 481.27 | 2.09 | 2.09 |
| 349.82 | 1.75 | 1.75 |
| 510.00 | 1.21 | 1.21 |
| 520.33 | 1.07 | 1.07 |
| 463.33 | 1.77 | 1.77 |
| 553.02 | 2.12 | 2.12 |
| 538.99 | 1.43 | 1.43 |
| 553.02 | 1.82 | 1.82 |
| 567.05 | 2.21 | 2.21 |
| 567.05 | 0.33 | 0.33 |
| 581.08 | 0.72 | 0.72 |
| 595.10 | 1.11 | 1.11 |
| 581.08 | 0.72 | 0.72 |
| 595.10 | 1.11 | 1.11 |
| 610.12 | -0.08 | -0.08 |
| 793.35 | 1.21 | 1.21 |
| 906.51 | 1.89 | 1.89 |
| 1125.79 | ||
| 538.99 | 1.73 | 1.73 |
| 567.05 | 0.33 | 0.33 |
| 595.10 | 1.11 | 1.11 |
| 371.83 | 2.00 | 2.00 |
| 463.28 | 1.96 | 1.96 |