Basic Information
ID: ALA1057723
Type: Functional
Description: Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Prokineticin receptor 1(ALA5649)
Document: ALA1151885
Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1057723
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 455.49 | 0.74 | 0.74 |
| 456.38 | 2.24 | 2.24 |
| 389.46 | 0.16 | 0.16 |
| 453.50 | 0.41 | 0.41 |
| 448.49 | 0.28 | 0.28 |
| 454.49 | -0.19 | -0.19 |
| 467.53 | 0.61 | 0.61 |
| 411.44 | 0.54 | 0.54 |
| 441.47 | 0.54 | 0.54 |
| 492.37 | 1.71 | 1.71 |
| 453.50 | 0.41 | 0.41 |
| 457.92 | 1.06 | 1.06 |
| 439.48 | 0.11 | 0.11 |
| 403.83 | 0.58 | 0.58 |
| 423.48 | 0.41 | 0.41 |
| 453.50 | 0.41 | 0.41 |
| 506.39 | 2.10 | 2.10 |
| 459.55 | 0.56 | 0.56 |
| 437.50 | 0.60 | 0.60 |
| 439.48 | 0.11 | 0.11 |
| 427.90 | 1.05 | 1.05 |
| 528.35 | 2.30 | 2.30 |
| 399.41 | -0.06 | -0.06 |
| 456.44 | 0.44 | 0.44 |
| 520.42 | 2.49 | 2.49 |