Basic Information
ID: ALA1060868
Type: Functional
Description: Antagonist activity at human CLR expressed in HEK293 cells coexpressing human RAMP1 assessed as inhibition of human CGRPalpha-induced cAMP production after 30 mins by scintillation proximity assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Calcitonin gene-related peptide type 1 receptor(ALA3798)
Document: ALA1153066
Antagonist activity at human CLR expressed in HEK293 cells coexpressing human RAMP1 assessed as inhibition of human CGRPalpha-induced cAMP production after 30 mins by scintillation proximity assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1060868
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 566.53 | 3.69 | 3.69 |
| 480.48 | 1.78 | 1.78 |
| 463.50 | 3.16 | 3.16 |
| 479.54 | 3.13 | 3.13 |
| 493.57 | 3.74 | 3.74 |
| 477.52 | 3.18 | 3.18 |
| 479.54 | 3.34 | 3.34 |
| 465.51 | 2.95 | 2.95 |
| 479.54 | 2.98 | 2.98 |
| 488.50 | 0.75 | 0.75 |