Basic Information
ID: ALA1062746
Type: Binding
Description: Inhibition of ALK5 expressed in CHO cells assessed as inhibition of TGF-beta-induced Smad2 phosphorylation at 1 uM
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA1062746
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 451.40 | 5.05 | 5.05 |
| 401.40 | 4.17 | 4.17 |
| 358.38 | 3.84 | 3.84 |
| 398.42 | 3.47 | 3.47 |
| 309.39 | 4.68 | 4.68 |
| 401.40 | 4.17 | 4.17 |
| 398.42 | 3.74 | 3.74 |
| 390.42 | 3.49 | 3.49 |
| 413.43 | 4.04 | 4.04 |
| 387.41 | 4.45 | 4.45 |
| 412.45 | 3.78 | 3.78 |
| 349.43 | 4.31 | 4.31 |
| 384.41 | 4.93 | 4.93 |
| 384.40 | 3.43 | 3.43 |
| 402.38 | 4.77 | 4.77 |
| 382.42 | 4.49 | 4.49 |
| 417.44 | 4.46 | 4.46 |
| 380.41 | 4.51 | 4.51 |
| 394.43 | 4.55 | 4.55 |
| 375.38 | 4.58 | 4.58 |
| 387.40 | 3.42 | 3.42 |
| 398.42 | 3.74 | 3.74 |
| 335.41 | 4.27 | 4.27 |
| 339.41 | 4.69 | 4.69 |
| 401.40 | 4.17 | 4.17 |
| 383.38 | 4.95 | 4.95 |
| 366.38 | 4.20 | 4.20 |
| 383.38 | 4.95 | 4.95 |
| 373.39 | 4.15 | 4.15 |
| 372.40 | 4.15 | 4.15 |
| 402.43 | 4.16 | 4.16 |
| 388.40 | 4.57 | 4.57 |
| 380.41 | 4.51 | 4.51 |
| 400.44 | 3.72 | 3.72 |
| 399.43 | 5.23 | 5.23 |
| 384.40 | 3.43 | 3.43 |
| 384.40 | 3.43 | 3.43 |
| 354.39 | 4.92 | 4.92 |
| 383.38 | 4.95 | 4.95 |
| 383.41 | 4.03 | 4.03 |