Basic Information
ID: ALA1063050
Type: Functional
Description: Inhibition of melanin synthesis in NHEM cells assessed as [14C]thiouracil incorporation after 72 hrs by liquid scintillation counting
Organism: Homo sapiens
Cell type: NHEM
Activity Charts
Bioactivity
Activity Types for Assay ALA1063050
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.24 | 2.58 | 2.58 |
| 110.11 | 1.10 | 1.10 |
| 272.25 | -1.43 | -1.43 |
| 324.38 | 4.31 | 4.31 |
| 392.50 | 5.72 | 5.72 |
| 408.49 | 5.53 | 5.53 |
| 406.52 | 6.12 | 6.12 |
| 410.51 | 4.61 | 4.61 |
| 330.34 | 3.06 | 3.06 |
| 370.40 | 4.23 | 4.23 |
| 368.43 | 4.53 | 4.53 |
| 366.37 | 4.62 | 4.62 |
| 758.86 | 10.00 | 10.00 |
| 476.61 | 7.04 | 7.04 |
| 392.50 | 5.72 | 5.72 |
| 368.39 | 4.00 | 4.00 |
| 408.49 | 4.79 | 4.79 |
| 492.61 | 6.01 | 6.01 |
| 354.40 | 4.22 | 4.22 |
| 406.48 | 5.40 | 5.40 |
| 392.50 | 5.82 | 5.82 |
| 408.49 | 4.79 | 4.79 |
| 356.42 | 3.40 | 3.40 |
| 406.52 | 6.03 | 6.03 |
| 352.39 | 4.92 | 4.92 |
| 460.61 | 7.33 | 7.33 |
| 390.48 | 5.69 | 5.69 |
| 492.61 | 6.74 | 6.74 |
| 356.42 | 3.40 | 3.40 |
| 354.40 | 3.37 | 3.37 |
| 316.31 | 3.54 | 3.54 |
| 422.52 | 5.73 | 5.73 |
| 406.52 | 6.03 | 6.03 |
| 352.39 | 4.19 | 4.19 |
| 490.60 | 6.71 | 6.71 |
| 476.61 | 6.30 | 6.30 |
| 342.39 | 3.10 | 3.10 |
| 452.55 | 5.74 | 5.74 |
| 352.43 | 4.83 | 4.83 |
| 350.37 | 4.89 | 4.89 |
| 420.46 | 5.83 | 5.83 |
| 338.40 | 4.62 | 4.62 |
| 356.42 | 3.41 | 3.41 |
| 354.40 | 4.22 | 4.22 |
| 458.60 | 7.30 | 7.30 |
| 422.52 | 5.48 | 5.48 |
| 368.43 | 4.53 | 4.53 |
| 338.40 | 4.52 | 4.52 |
| 812.96 | 11.21 | 11.21 |
| 390.48 | 5.69 | 5.69 |
| 492.61 | 6.74 | 6.74 |
| 370.45 | 3.70 | 3.70 |
| 352.34 | 4.32 | 4.32 |
| 758.86 | 10.00 | 10.00 |
| 812.96 | 11.21 | 11.21 |
| 406.48 | 5.50 | 5.50 |