Basic Information
ID: ALA1063427
Type: Binding
Description: Inhibition of mouse liver microsome 11betaHSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone into [3H]cortisol by scintillation proximity assay
Organism: Mus musculus
Tissue: Liver
Cell type: HEK293
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA1063427
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 822.94 | 2.25 | 2.25 |
| 371.38 | 2.61 | 2.61 |
| 553.62 | 4.28 | 4.28 |
| 583.65 | 4.29 | 4.29 |
| 527.59 | 3.43 | 3.43 |
| 539.64 | 4.64 | 4.64 |
| 553.66 | 4.95 | 4.95 |
| 545.68 | 5.02 | 5.02 |
| 589.70 | 5.79 | 5.79 |
| 525.61 | 4.64 | 4.64 |
| 607.63 | 5.66 | 5.66 |
| 540.62 | 4.03 | 4.03 |
| 595.70 | 5.23 | 5.23 |
| 529.60 | 4.23 | 4.23 |
| 560.05 | 5.30 | 5.30 |
| 595.74 | 5.94 | 5.94 |
| 543.58 | 3.87 | 3.87 |