Basic Information
ID: ALA1064390
Type: Functional
Description: Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CCL39
Target: Calcium sensing receptor(ALA1878)
Document: ALA1157601
Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1064390
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 436.56 | 5.81 | 5.81 |
| 450.58 | 6.37 | 6.37 |
| 438.53 | 5.26 | 5.26 |
| 452.55 | 5.65 | 5.65 |
| 482.54 | 4.71 | 4.71 |
| 422.53 | 5.56 | 5.56 |
| 436.56 | 5.81 | 5.81 |
| 410.52 | 5.67 | 5.67 |
| 412.53 | 5.89 | 5.89 |
| 424.54 | 5.89 | 5.89 |
| 438.53 | 5.26 | 5.26 |
| 482.58 | 5.65 | 5.65 |
| 482.54 | 4.71 | 4.71 |
| 468.55 | 4.62 | 4.62 |
| 484.62 | 5.99 | 5.99 |
| 349.48 | 5.20 | 5.20 |
| 377.53 | 5.61 | 5.61 |
| 363.51 | 5.59 | 5.59 |
| 405.59 | 6.39 | 6.39 |
| 361.49 | 5.37 | 5.37 |
| 375.52 | 5.39 | 5.39 |
| 359.47 | 4.81 | 4.81 |
| 397.52 | 4.84 | 4.84 |
| 411.55 | 6.38 | 6.38 |
| 563.70 | 4.43 | 4.43 |
| 607.75 | 4.45 | 4.45 |
| 634.82 | 4.76 | 4.76 |
| 336.44 | 4.78 | 4.78 |
| 294.35 | 3.65 | 3.65 |
| 308.38 | 3.96 | 3.96 |
| 322.41 | 4.22 | 4.22 |
| 334.42 | 4.53 | 4.53 |
| 350.46 | 4.95 | 4.95 |
| 370.45 | 5.32 | 5.32 |
| 352.43 | 4.44 | 4.44 |
| 352.39 | 3.44 | 3.44 |
| 338.36 | 3.35 | 3.35 |
| 322.41 | 4.47 | 4.47 |
| 350.46 | 5.17 | 5.17 |
| 364.49 | 5.56 | 5.56 |
| 364.49 | 5.56 | 5.56 |
| 378.52 | 5.95 | 5.95 |
| 362.47 | 5.33 | 5.33 |
| 376.50 | 5.72 | 5.72 |
| 360.46 | 4.78 | 4.78 |
| 374.48 | 5.17 | 5.17 |
| 408.50 | 5.25 | 5.25 |
| 422.53 | 5.56 | 5.56 |