Basic Information
ID: ALA1066384
Type: Functional
Description: Agonist activity at human alpha7 nAChR/mouse 5HT3 chimeric receptor expressed in SH-EP1 cells assessed as increase in intracellular calcium level relative to 100 uM nicotine
Cell type: SH-EP1
Activity Charts
Bioactivity
Activity Types for Assay ALA1066384
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 292.77 | 2.47 | 2.47 |
| 272.35 | 2.07 | 2.07 |
| 286.38 | 2.63 | 2.63 |
| 312.42 | 3.16 | 3.16 |
| 320.40 | 3.17 | 3.17 |
| 338.39 | 3.31 | 3.31 |
| 274.32 | 1.52 | 1.52 |
| 336.40 | 3.30 | 3.30 |
| 327.43 | 2.50 | 2.50 |
| 313.41 | 2.11 | 2.11 |
| 323.19 | 2.27 | 2.27 |
| 278.74 | 2.16 | 2.16 |
| 262.29 | 1.65 | 1.65 |
| 258.32 | 1.82 | 1.82 |
| 272.35 | 2.07 | 2.07 |
| 320.40 | 3.17 | 3.17 |
| 258.32 | 1.82 | 1.82 |
| 278.74 | 2.16 | 2.16 |
| 320.40 | 3.17 | 3.17 |
| 258.32 | 1.82 | 1.82 |
| 269.31 | 1.38 | 1.38 |
| 310.36 | 1.90 | 1.90 |
| 321.38 | 2.57 | 2.57 |
| 336.40 | 3.30 | 3.30 |
| 276.31 | 1.95 | 1.95 |