Basic Information
ID: ALA1067650
Type: Binding
Description: Inhibition of GARFtase in human KB cells assessed as [14C]glycine incorporation in to [14C]FGAR in folate free RPMI medium with 2 nM LCV by in-situassay
Organism: Homo sapiens
Cell type: KB
Activity Charts
Bioactivity
Activity Types for Assay ALA1067650
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 443.46 | 0.62 | 0.62 |
| 455.47 | 1.45 | 1.45 |
| 427.42 | 0.67 | 0.67 |
| 472.52 | 2.18 | 2.18 |
| 461.50 | 1.51 | 1.51 |
| 475.53 | 1.90 | 1.90 |