Inhibition of N type calcium channel alpha-1b/alpha-2-delta-1/beta-1b expressed in HEK293 cells at holding potential of -100 mV by whole-cell patch cl...

Basic Information

ID: ALA1068015

Type: Binding

Description: Inhibition of N type calcium channel alpha-1b/alpha-2-delta-1/beta-1b expressed in HEK293 cells at holding potential of -100 mV by whole-cell patch clamp method

Format: BAO_0000219

Cell type: HEK293

Target: N-type calcium channel alpha-1b/alpha2delta-1/beta-1b(ALA4106160)

Document: ALA1156924

Inhibition of N type calcium channel alpha-1b/alpha-2-delta-1/beta-1b expressed in HEK293 cells at holding potential of -100 mV by whole-cell patch clamp method: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA1068015

IC50

Total(50)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
460.62	6.14	6.14
528.62	7.16	7.16
528.62	7.16	7.16
528.62	7.16	7.16
495.07	6.80	6.80
495.07	6.80	6.80
495.07	6.80	6.80
495.07	6.80	6.80
495.07	6.80	6.80
478.61	6.28	6.28
474.65	6.45	6.45
490.65	6.15	6.15
520.67	6.16	6.16
550.70	6.17	6.17
529.51	7.45	7.45
529.51	7.45	7.45
529.51	7.45	7.45
529.51	7.45	7.45
529.51	7.45	7.45
488.68	6.76	6.76
520.67	6.16	6.16
461.61	5.89	5.89
496.05	6.55	6.55
496.05	6.55	6.55
496.05	6.55	6.55
530.50	7.20	7.20
530.50	7.20	7.20
489.66	6.51	6.51
461.61	5.76	5.76
496.05	6.41	6.41
496.05	6.41	6.41
496.05	6.41	6.41
530.50	7.07	7.07
530.50	7.07	7.07
489.66	6.38	6.38
461.61	5.76	5.76
496.05	6.41	6.41
496.05	6.41	6.41
496.05	6.41	6.41
530.50	7.07	7.07
530.50	7.07	7.07
489.66	6.38	6.38
467.66	5.09	5.09
481.68	5.44	5.44
481.68	5.44	5.44
516.13	6.09	6.09
499.67	5.58	5.58
391.56	3.35	3.35
391.56	3.49	3.49
405.59	3.69	3.69