Basic Information
ID: ALA1068091
Type: Functional
Description: Antagonist activity at human alpha4beta4 nAChR receptor expressed in human SH-SY5Y cells assessed as inhibition of carbamylcholine-induced 86Rb+ efflux by liquid scintillation counting
Organism: Homo sapiens
Cell type: SH-SY5Y
Activity Charts
Bioactivity
Activity Types for Assay ALA1068091
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 239.75 | 3.30 | 3.30 |
| 241.28 | 2.92 | 2.92 |
| 274.19 | 3.95 | 3.95 |
| 253.77 | 3.61 | 3.61 |
| 298.22 | 3.72 | 3.72 |
| 302.24 | 4.73 | 4.73 |
| 274.19 | 3.95 | 3.95 |
| 253.77 | 3.69 | 3.69 |
| 253.77 | 3.64 | 3.64 |
| 211.69 | 2.47 | 2.47 |
| 267.80 | 4.08 | 4.08 |
| 251.76 | 3.40 | 3.40 |
| 211.33 | 2.71 | 2.71 |
| 253.77 | 3.55 | 3.55 |
| 223.29 | 2.79 | 2.79 |
| 284.20 | 3.41 | 3.41 |
| 219.33 | 2.95 | 2.95 |
| 251.76 | 3.44 | 3.44 |
| 239.75 | 3.30 | 3.30 |
| 284.20 | 3.41 | 3.41 |
| 219.33 | 2.95 | 2.95 |
| 288.22 | 4.34 | 4.34 |
| 235.33 | 2.65 | 2.65 |
| 250.30 | 2.55 | 2.55 |
| 235.30 | 2.93 | 2.93 |
| 296.21 | 3.55 | 3.55 |
| 231.34 | 3.10 | 3.10 |
| 247.34 | 2.80 | 2.80 |
| 262.31 | 2.70 | 2.70 |
| 235.30 | 2.88 | 2.88 |
| 296.21 | 3.51 | 3.51 |
| 231.34 | 3.05 | 3.05 |
| 247.34 | 2.75 | 2.75 |
| 262.31 | 2.65 | 2.65 |