Basic Information
ID: ALA1068493
Type: Binding
Description: Inhibition of HDM2 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of HDM2 binding to p53 protein by fluorescence anisotropy competition method
Format: BAO_0000019
Target: p53-binding protein Mdm-2(ALA5023)
Document: ALA1153086
Inhibition of HDM2 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of HDM2 binding to p53 protein by fluorescence anisotropy competition method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1068493
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 917.55 | 3.71 | 3.71 |
| 931.58 | 4.10 | 4.10 |
| 966.02 | 4.76 | 4.76 |
| 945.60 | 4.49 | 4.49 |
| 990.05 | 4.60 | 4.60 |
| 1004.08 | ||
| 990.05 | 4.60 | 4.60 |
| 1054.92 | ||
| 1068.95 | ||
| 1004.08 | ||
| 1035.05 | ||
| 1020.08 | ||
| 1082.98 | ||
| 1102.97 | ||
| 1132.99 | ||
| 1147.96 | ||
| 1181.86 | ||
| 1084.35 | ||
| 1099.27 | ||
| 1046.23 | ||
| 1205.19 | ||
| 1204.20 | ||
| 1149.08 | ||
| 1184.13 | ||
| 1038.36 | ||
| 1131.28 | ||
| 1052.39 | ||
| 1163.11 | ||
| 1109.02 | ||
| 1164.14 | ||
| 1103.23 |