Basic Information
ID: ALA1069873
Type: Functional
Description: Allosteric modulation of human muscarinic M1 receptor expressed in CHO cells assessed as effect on acetylcholine-induced calcium mobilization by FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Muscarinic acetylcholine receptor M1(ALA216)
Document: ALA1153216
Allosteric modulation of human muscarinic M1 receptor expressed in CHO cells assessed as effect on acetylcholine-induced calcium mobilization by FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1069873
IP
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 309.32 | 2.76 | 2.76 |
| 373.38 | 4.55 | 4.55 |
| 399.27 | 3.92 | 3.92 |
| 363.29 | 3.65 | 3.65 |
| 381.28 | 3.79 | 3.79 |
| 381.28 | 3.79 | 3.79 |
| 399.27 | 3.92 | 3.92 |
| 355.39 | 4.42 | 4.42 |
| 373.38 | 4.55 | 4.55 |
| 391.37 | 4.69 | 4.69 |
| 373.38 | 4.55 | 4.55 |
| 389.84 | 5.07 | 5.07 |
| 398.39 | 4.43 | 4.43 |
| 398.39 | 4.43 | 4.43 |
| 460.46 | 3.28 | 3.28 |
| 456.47 | 4.45 | 4.45 |
| 412.42 | 5.04 | 5.04 |
| 424.43 | 5.10 | 5.10 |
| 388.40 | 4.14 | 4.14 |
| 416.45 | 4.62 | 4.62 |
| 430.48 | 4.62 | 4.62 |
| 404.40 | 3.44 | 3.44 |
| 374.37 | 3.95 | 3.95 |
| 389.39 | 3.53 | 3.53 |
| 403.41 | 3.99 | 3.99 |
| 472.52 | 3.70 | 3.70 |
| 404.40 | 3.96 | 3.96 |
| 279.30 | 2.75 | 2.75 |
| 297.29 | 2.89 | 2.89 |
| 297.29 | 2.89 | 2.89 |
| 315.27 | 3.03 | 3.03 |
| 293.32 | 2.94 | 2.94 |
| 311.31 | 3.08 | 3.08 |
| 374.37 | 3.95 | 3.95 |
| 417.44 | 4.02 | 4.02 |
| 375.36 | 3.34 | 3.34 |
| 405.39 | 3.35 | 3.35 |
| 363.35 | 3.28 | 3.28 |
| 311.31 | 3.08 | 3.08 |
| 329.30 | 3.22 | 3.22 |
| 305.33 | 3.24 | 3.24 |
| 323.32 | 3.38 | 3.38 |
| 323.32 | 3.38 | 3.38 |
| 341.31 | 3.52 | 3.52 |
| 381.34 | 3.42 | 3.42 |
| 377.38 | 3.29 | 3.29 |
| 376.18 | 3.65 | 3.65 |
| 394.17 | 3.79 | 3.79 |
| 394.17 | 3.79 | 3.79 |
| 412.16 | 3.93 | 3.93 |
| 315.27 | 3.03 | 3.03 |
| 333.26 | 3.17 | 3.17 |
| 333.26 | 3.17 | 3.17 |
| 351.25 | 3.30 | 3.30 |
| 319.36 | 3.63 | 3.63 |
| 337.35 | 3.76 | 3.76 |
| 337.35 | 3.76 | 3.76 |
| 355.34 | 3.90 | 3.90 |
| 357.39 | 2.15 | 2.15 |
| 375.38 | 2.29 | 2.29 |
| 375.38 | 2.29 | 2.29 |
| 393.37 | 2.43 | 2.43 |
| 322.32 | 1.85 | 1.85 |
| 340.31 | 1.99 | 1.99 |
| 340.31 | 1.99 | 1.99 |
| 358.30 | 2.13 | 2.13 |
| 327.31 | 2.90 | 2.90 |
| 327.31 | 2.90 | 2.90 |
| 345.30 | 3.03 | 3.03 |
| 309.32 | 2.76 | 2.76 |
| 327.31 | 2.90 | 2.90 |
| 327.31 | 2.90 | 2.90 |
| 345.30 | 3.03 | 3.03 |
| 347.29 | 3.77 | 3.77 |
| 365.28 | 3.91 | 3.91 |
| 365.28 | 3.91 | 3.91 |
| 383.27 | 4.05 | 4.05 |
| 347.29 | 3.77 | 3.77 |
| 365.28 | 3.91 | 3.91 |
| 365.28 | 3.91 | 3.91 |
| 383.27 | 4.05 | 4.05 |
| 347.29 | 3.77 | 3.77 |
| 365.28 | 3.91 | 3.91 |
| 365.28 | 3.91 | 3.91 |
| 383.27 | 4.05 | 4.05 |
| 363.29 | 3.65 | 3.65 |
| 381.28 | 3.79 | 3.79 |
| 381.28 | 3.79 | 3.79 |