Basic Information
ID: ALA1070011
Type: Binding
Description: Inhibition of SHP2 Src homology-2 domain expressed in Escherichia coli BL21 (DE3) assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH 7 by spectrophotometry
Format: BAO_0000019
Target: Protein-tyrosine phosphatase 2C(ALA3864)
Document: ALA1157613
Inhibition of SHP2 Src homology-2 domain expressed in Escherichia coli BL21 (DE3) assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH 7 by spectrophotometry: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1070011
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 557.61 | 6.20 | 6.20 |
| 552.59 | 3.98 | 3.98 |
| 555.59 | 5.39 | 5.39 |
| 524.56 | 4.76 | 4.76 |
| 615.72 | 7.51 | 7.51 |
| 291.31 | 3.23 | 3.23 |
| 543.58 | 5.81 | 5.81 |
| 571.64 | 6.59 | 6.59 |
| 481.51 | 4.54 | 4.54 |