Basic Information
ID: ALA1070026
Type: Binding
Description: Inhibition of SHP2-dependent ERK1/2 activation in EGF-stimulated mouse NIH/3T3 cells assessed as phosphorylated ERK1/2 level at 10 uM treated for 3 hrs before EGF challenge measured after 60 mins of EGF stimulation by immunoblot analysis
Format: BAO_0000219
Organism: Mus musculus
Cell type: NIH3T3
Target: Protein-tyrosine phosphatase 2C(ALA2620)
Document: ALA1157613
Inhibition of SHP2-dependent ERK1/2 activation in EGF-stimulated mouse NIH/3T3 cells assessed as phosphorylated ERK1/2 level at 10 uM treated for 3 hrs before EGF challenge measured after 60 mins of EGF stimulation by immunoblot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1070026
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 557.61 | 6.20 | 6.20 |