Basic Information
ID: ALA1070311
Type: Functional
Description: Antagonist activity at mouse EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase intracellular calcium level in presence of 1% BSA by fluorimetry
Organism: Mus musculus
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA1070311
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 445.56 | 5.80 | 5.80 |
| 475.59 | 5.81 | 5.81 |
| 475.59 | 5.81 | 5.81 |
| 475.59 | 5.81 | 5.81 |
| 463.55 | 5.94 | 5.94 |
| 463.55 | 5.94 | 5.94 |
| 463.55 | 5.94 | 5.94 |
| 480.00 | 6.45 | 6.45 |
| 480.00 | 6.45 | 6.45 |
| 513.56 | 6.82 | 6.82 |
| 513.56 | 6.82 | 6.82 |
| 473.61 | 6.42 | 6.42 |
| 489.61 | 6.12 | 6.12 |
| 477.58 | 6.25 | 6.25 |
| 473.61 | 6.42 | 6.42 |
| 505.61 | 5.82 | 5.82 |
| 503.60 | 5.57 | 5.57 |
| 477.58 | 6.25 | 6.25 |
| 493.58 | 5.95 | 5.95 |
| 481.54 | 6.08 | 6.08 |
| 531.55 | 6.96 | 6.96 |
| 481.54 | 6.08 | 6.08 |
| 531.55 | 6.96 | 6.96 |
| 497.99 | 6.59 | 6.59 |
| 491.60 | 6.56 | 6.56 |
| 491.60 | 6.56 | 6.56 |
| 491.60 | 6.56 | 6.56 |
| 508.06 | 7.07 | 7.07 |
| 508.06 | 7.07 | 7.07 |
| 508.06 | 7.07 | 7.07 |
| 498.62 | 6.29 | 6.29 |
| 498.62 | 6.29 | 6.29 |
| 498.62 | 6.29 | 6.29 |
| 487.64 | 6.73 | 6.73 |
| 487.64 | 6.73 | 6.73 |
| 487.64 | 6.73 | 6.73 |
| 503.64 | 6.43 | 6.43 |
| 484.60 | 5.98 | 5.98 |
| 500.60 | 5.68 | 5.68 |
| 488.56 | 5.81 | 5.81 |
| 502.59 | 6.12 | 6.12 |
| 530.62 | 5.69 | 5.69 |
| 509.59 | 6.70 | 6.70 |
| 509.59 | 6.70 | 6.70 |
| 509.59 | 6.70 | 6.70 |
| 509.59 | 6.70 | 6.70 |
| 509.59 | 6.70 | 6.70 |
| 509.59 | 6.70 | 6.70 |
| 459.59 | 6.11 | 6.11 |
| 459.59 | 6.11 | 6.11 |
| 459.59 | 6.11 | 6.11 |