Basic Information
ID: ALA1071425
Type: Binding
Description: Inhibition of rat liver DHFR by spectrophotometric assay
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA1071425
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 324.17 | 3.31 | 3.31 |
| 337.21 | 3.07 | 3.07 |
| 314.35 | 1.75 | 1.75 |
| 358.62 | 3.96 | 3.96 |
| 328.38 | 1.78 | 1.78 |
| 340.24 | 3.72 | 3.72 |
| 331.40 | 2.43 | 2.43 |
| 323.19 | 3.04 | 3.04 |
| 319.37 | 3.18 | 3.18 |
| 306.32 | 3.12 | 3.12 |
| 347.38 | 3.79 | 3.79 |
| 272.33 | 2.68 | 2.68 |
| 372.64 | 3.98 | 3.98 |
| 324.17 | 3.31 | 3.31 |
| 322.39 | 3.83 | 3.83 |
| 331.38 | 3.67 | 3.67 |
| 305.34 | 3.15 | 3.15 |
| 305.34 | 3.15 | 3.15 |
| 322.39 | 3.83 | 3.83 |
| 308.39 | 2.61 | 2.61 |
| 226.24 | 1.18 | 1.18 |
| 342.40 | 2.53 | 2.53 |
| 314.35 | 1.75 | 1.75 |
| 254.30 | 1.73 | 1.73 |
| 284.32 | 1.74 | 1.74 |
| 344.38 | 1.76 | 1.76 |
| 295.13 | 2.49 | 2.49 |
| 286.30 | 1.20 | 1.20 |
| 316.32 | 1.21 | 1.21 |
| 316.32 | 1.21 | 1.21 |
| 286.30 | 1.20 | 1.20 |
| 302.34 | 2.85 | 2.85 |
| 302.29 | 0.91 | 0.91 |
| 286.30 | 1.20 | 1.20 |
| 276.30 | 2.34 | 2.34 |
| 322.40 | 2.96 | 2.96 |
| 315.34 | 1.15 | 1.15 |
| 316.32 | 1.21 | 1.21 |
| 314.35 | 2.68 | 2.68 |
| 286.30 | 1.20 | 1.20 |
| 316.32 | 1.21 | 1.21 |
| 240.27 | 1.11 | 1.11 |
| 305.79 | 3.24 | 3.24 |
| 305.79 | 3.24 | 3.24 |
| 301.38 | 2.59 | 2.59 |
| 301.38 | 2.59 | 2.59 |
| 331.40 | 2.60 | 2.60 |
| 340.24 | 3.89 | 3.89 |
| 301.38 | 2.59 | 2.59 |
| 325.44 | 3.46 | 3.46 |
| 305.79 | 3.24 | 3.24 |
| 325.44 | 3.46 | 3.46 |
| 305.79 | 3.24 | 3.24 |
| 340.24 | 3.89 | 3.89 |
| 331.40 | 2.60 | 2.60 |
| 271.35 | 2.58 | 2.58 |
| 336.23 | 3.60 | 3.60 |
| 327.39 | 2.31 | 2.31 |
| 357.41 | 2.32 | 2.32 |
| 373.46 | 3.88 | 3.88 |
| 321.43 | 3.18 | 3.18 |
| 321.43 | 3.18 | 3.18 |
| 267.34 | 2.30 | 2.30 |
| 322.42 | 2.64 | 2.64 |
| 325.44 | 3.29 | 3.29 |
| 325.44 | 3.29 | 3.29 |
| 331.29 | 1.11 | 1.11 |
| 355.40 | 4.31 | 4.31 |
| 343.39 | 3.57 | 3.57 |
| 372.43 | 4.13 | 4.13 |
| 359.39 | 3.06 | 3.06 |
| 389.42 | 3.93 | 3.93 |
| 386.46 | 4.15 | 4.15 |
| 348.43 | 4.35 | 4.35 |
| 348.43 | 4.35 | 4.35 |
| 348.43 | 4.35 | 4.35 |
| 364.43 | 4.47 | 4.47 |
| 364.43 | 4.47 | 4.47 |
| 364.43 | 4.47 | 4.47 |
| 325.44 | 3.46 | 3.46 |