Basic Information
ID: ALA1071707
Type: Binding
Description: Inhibition of human ROCK2 by homogenous luciferase assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Rho-associated protein kinase 2(ALA2973)
Document: ALA1157712
Inhibition of human ROCK2 by homogenous luciferase assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1071707
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 291.38 | 1.22 | 1.22 |
| 319.43 | 1.92 | 1.92 |
| 247.34 | 2.17 | 2.17 |
| 461.58 | 2.30 | 2.30 |
| 425.53 | 3.35 | 3.35 |
| 425.53 | 3.60 | 3.60 |
| 417.51 | 3.94 | 3.94 |
| 417.51 | 3.94 | 3.94 |
| 419.48 | 3.34 | 3.34 |
| 431.54 | 4.25 | 4.25 |
| 451.95 | 4.59 | 4.59 |
| 485.51 | 4.96 | 4.96 |
| 505.92 | 5.48 | 5.48 |
| 412.49 | 3.80 | 3.80 |
| 405.50 | 3.00 | 3.00 |
| 440.54 | 3.15 | 3.15 |
| 405.50 | 3.00 | 3.00 |
| 405.50 | 3.60 | 3.60 |
| 405.50 | 3.00 | 3.00 |
| 425.49 | 3.78 | 3.78 |
| 427.51 | 4.19 | 4.19 |
| 399.45 | 3.59 | 3.59 |
| 461.95 | 4.85 | 4.85 |
| 445.52 | 3.42 | 3.42 |
| 479.97 | 4.07 | 4.07 |
| 445.52 | 3.42 | 3.42 |
| 443.51 | 3.01 | 3.01 |
| 419.48 | 3.00 | 3.00 |
| 356.42 | 2.77 | 2.77 |
| 398.46 | 2.54 | 2.54 |
| 399.45 | 3.25 | 3.25 |
| 378.43 | 2.79 | 2.79 |
| 389.46 | 2.99 | 2.99 |
| 389.46 | 2.99 | 2.99 |
| 403.44 | 2.71 | 2.71 |
| 387.48 | 3.60 | 3.60 |
| 441.49 | 4.43 | 4.43 |
| 425.53 | 2.75 | 2.75 |
| 445.52 | 3.53 | 3.53 |
| 425.53 | 2.75 | 2.75 |
| 445.52 | 3.53 | 3.53 |
| 439.56 | 3.10 | 3.10 |
| 459.55 | 3.87 | 3.87 |
| 447.54 | 3.95 | 3.95 |
| 420.47 | 3.38 | 3.38 |
| 425.53 | 2.75 | 2.75 |
| 425.53 | 3.00 | 3.00 |
| 411.50 | 3.08 | 3.08 |
| 426.52 | 3.47 | 3.47 |