Basic Information
ID: ALA1071957
Type: Binding
Description: Inhibition of SCD1 in human 293A cells assessed as conversion of [14C]stearate to [14C]oleate after 60 mins in presence of S9 microsomal fraction
Format: BAO_0000219
Organism: Homo sapiens
Cell type: S9
Target: Acyl-CoA desaturase(ALA5555)
Document: ALA1153242
Inhibition of SCD1 in human 293A cells assessed as conversion of [14C]stearate to [14C]oleate after 60 mins in presence of S9 microsomal fraction: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1071957
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 444.54 | 3.35 | 3.35 |
| 478.52 | 2.93 | 2.93 |
| 478.52 | 2.93 | 2.93 |
| 478.52 | 2.93 | 2.93 |
| 490.56 | 2.80 | 2.80 |
| 463.51 | 2.84 | 2.84 |
| 479.97 | 3.35 | 3.35 |
| 459.55 | 3.01 | 3.01 |
| 513.52 | 3.72 | 3.72 |
| 481.50 | 2.98 | 2.98 |
| 498.51 | 4.58 | 4.58 |
| 507.52 | 4.63 | 4.63 |
| 521.55 | 4.64 | 4.64 |
| 508.50 | 4.90 | 4.90 |
| 522.53 | 5.09 | 5.09 |
| 494.48 | 4.97 | 4.97 |
| 442.52 | 2.97 | 2.97 |
| 456.55 | 3.36 | 3.36 |
| 444.49 | 2.55 | 2.55 |
| 458.52 | 2.48 | 2.48 |
| 458.52 | 2.94 | 2.94 |
| 458.52 | 2.69 | 2.69 |
| 460.53 | 2.80 | 2.80 |
| 474.56 | 3.45 | 3.45 |
| 460.53 | 2.27 | 2.27 |
| 442.52 | 3.38 | 3.38 |
| 444.54 | 3.30 | 3.30 |
| 444.54 | 3.05 | 3.05 |
| 478.52 | 2.93 | 2.93 |