Basic Information
ID: ALA1072836
Type: Binding
Description: Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as drug level required for twofold increase in Wnt signaling after 16 to 18 hrs by luciferase reporter gene assay
Organism: Homo sapiens
Cell type: U2OS
Activity Charts
Bioactivity
Activity Types for Assay ALA1072836
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 645.72 | 4.21 | 4.21 |
| 645.72 | 4.21 | 4.21 |
| 545.61 | 2.56 | 2.56 |
| 545.61 | 2.56 | 2.56 |
| 587.04 | 4.77 | 4.77 |
| 620.59 | 5.14 | 5.14 |
| 595.67 | 4.19 | 4.19 |
| 553.58 | 3.52 | 3.52 |
| 553.58 | 3.52 | 3.52 |
| 553.58 | 3.52 | 3.52 |
| 588.03 | 4.17 | 4.17 |
| 621.58 | 4.54 | 4.54 |
| 596.65 | 3.58 | 3.58 |
| 622.69 | 4.12 | 4.12 |
| 638.69 | 3.35 | 3.35 |
| 659.75 | 4.45 | 4.45 |
| 673.78 | 4.84 | 4.84 |
| 645.72 | 4.06 | 4.06 |
| 645.72 | 4.06 | 4.06 |
| 559.63 | 2.81 | 2.81 |
| 573.66 | 3.20 | 3.20 |
| 545.61 | 2.42 | 2.42 |
| 545.61 | 2.42 | 2.42 |
| 505.54 | 1.77 | 1.77 |
| 506.52 | 2.37 | 2.37 |
| 520.55 | 2.76 | 2.76 |
| 548.56 | 2.67 | 2.67 |
| 562.59 | 3.06 | 3.06 |
| 506.57 | 2.66 | 2.66 |
| 534.62 | 3.44 | 3.44 |
| 588.65 | 3.67 | 3.67 |
| 632.66 | 3.37 | 3.37 |
| 632.66 | 3.37 | 3.37 |
| 613.66 | 3.54 | 3.54 |
| 656.69 | 2.85 | 2.85 |
| 568.60 | 4.18 | 4.18 |
| 568.60 | 4.18 | 4.18 |
| 552.60 | 4.12 | 4.12 |
| 587.04 | 4.77 | 4.77 |
| 587.04 | 4.77 | 4.77 |