Assay Report Card

Basic Information

ID: ALA1072837

Type: Binding

Description: Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as drug level required for fourfold increase in Wnt signaling after 16 to 18 hrs by luciferase reporter gene assay

Organism: Homo sapiens

Cell type: U2OS

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
645.724.214.21
645.724.214.21
545.612.562.56
545.612.562.56
587.044.774.77
620.595.145.14
595.674.194.19
553.583.523.52
553.583.523.52
553.583.523.52
588.034.174.17
621.584.544.54
596.653.583.58
622.694.124.12
638.693.353.35
659.754.454.45
673.784.844.84
645.724.064.06
645.724.064.06
559.632.812.81
573.663.203.20
545.612.422.42
545.612.422.42
505.541.771.77
506.522.372.37
520.552.762.76
548.562.672.67
562.593.063.06
506.572.662.66
534.623.443.44
632.663.373.37
613.663.543.54
656.692.852.85
568.604.184.18
568.604.184.18
552.604.124.12
587.044.774.77
587.044.774.77