Basic Information
ID: ALA1073135
Type: Functional
Description: Agonist activity at human TGR5 receptor expressed in human U2-OS cells assessed as changes in response to cAMP level by MRE/CRE-driven luciferase reporter gene assay
Organism: Homo sapiens
Cell type: U2OS
Activity Charts
Bioactivity
Activity Types for Assay ALA1073135
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 375.26 | 5.62 | 5.62 |
| 361.23 | 5.23 | 5.23 |
| 375.26 | 5.54 | 5.54 |
| 395.67 | 5.89 | 5.89 |
| 498.60 | 6.41 | 6.41 |
| 354.84 | 5.20 | 5.20 |
| 326.78 | 4.58 | 4.58 |
| 354.84 | 5.14 | 5.14 |
| 368.86 | 5.53 | 5.53 |
| 368.86 | 5.70 | 5.70 |
| 382.89 | 5.88 | 5.88 |
| 394.78 | 5.60 | 5.60 |
| 410.78 | 5.48 | 5.48 |
| 351.79 | 4.45 | 4.45 |
| 369.85 | 4.65 | 4.65 |
| 368.82 | 4.78 | 4.78 |
| 404.88 | 3.98 | 3.98 |
| 384.82 | 4.37 | 4.37 |
| 344.77 | 4.72 | 4.72 |
| 344.77 | 4.72 | 4.72 |
| 344.77 | 4.72 | 4.72 |
| 361.23 | 5.23 | 5.23 |
| 361.23 | 5.23 | 5.23 |
| 340.81 | 4.89 | 4.89 |
| 340.81 | 4.89 | 4.89 |
| 340.81 | 4.89 | 4.89 |
| 356.81 | 4.59 | 4.59 |
| 356.81 | 4.59 | 4.59 |
| 356.81 | 4.59 | 4.59 |
| 394.78 | 5.60 | 5.60 |
| 394.78 | 5.60 | 5.60 |
| 394.78 | 5.60 | 5.60 |
| 326.78 | 4.58 | 4.58 |
| 395.67 | 5.89 | 5.89 |
| 379.22 | 5.37 | 5.37 |
| 347.20 | 5.21 | 5.21 |
| 375.26 | 5.62 | 5.62 |
| 389.28 | 6.01 | 6.01 |
| 389.28 | 6.01 | 6.01 |
| 387.27 | 5.77 | 5.77 |
| 347.20 | 4.93 | 4.93 |
| 375.26 | 5.49 | 5.49 |
| 389.28 | 6.05 | 6.05 |
| 389.28 | 5.88 | 5.88 |
| 387.27 | 5.80 | 5.80 |
| 389.28 | 5.88 | 5.88 |
| 417.34 | 6.83 | 6.83 |
| 373.24 | 5.16 | 5.16 |
| 340.81 | 3.76 | 3.76 |
| 340.81 | 4.83 | 4.83 |
| 356.81 | 4.59 | 4.59 |
| 356.81 | 4.59 | 4.59 |
| 344.77 | 4.72 | 4.72 |
| 344.77 | 4.72 | 4.72 |
| 344.77 | 4.72 | 4.72 |
| 361.23 | 5.23 | 5.23 |
| 361.23 | 5.23 | 5.23 |
| 405.68 | 5.34 | 5.34 |
| 452.68 | 5.18 | 5.18 |
| 340.81 | 4.89 | 4.89 |
| 340.81 | 4.89 | 4.89 |
| 340.81 | 4.89 | 4.89 |
| 356.81 | 4.59 | 4.59 |
| 375.26 | 5.54 | 5.54 |
| 375.26 | 5.54 | 5.54 |
| 395.67 | 5.89 | 5.89 |