Basic Information
ID: ALA1074804
Type: Binding
Description: Inhibition of TNF-alpha-induced NF-kappaB activity in human pNF-kappaB-luc-293 cells
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1074804
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 300.44 | 4.90 | 4.90 |
| 286.46 | 4.81 | 4.81 |
| 302.46 | 5.21 | 5.21 |
| 332.44 | 3.50 | 3.50 |
| 316.44 | 4.61 | 4.61 |
| 290.49 | 5.50 | 5.50 |
| 308.51 | 4.70 | 4.70 |
| 306.49 | 4.71 | 4.71 |
| 334.46 | 4.03 | 4.03 |
| 334.46 | 4.09 | 4.09 |
| 352.47 | 2.58 | 2.58 |
| 352.47 | 2.73 | 2.73 |
| 316.44 | 4.39 | 4.39 |
| 402.53 | 4.72 | 4.72 |
| 416.56 | 5.37 | 5.37 |
| 416.56 | 4.81 | 4.81 |
| 402.53 | 4.33 | 4.33 |
| 416.56 | 4.99 | 4.99 |
| 416.56 | 4.42 | 4.42 |
| 418.53 | 3.82 | 3.82 |
| 432.56 | 4.48 | 4.48 |
| 330.47 | 4.66 | 4.66 |
| 346.47 | 4.15 | 4.15 |
| 344.50 | 5.05 | 5.05 |
| 400.52 | 4.87 | 4.87 |
| 416.51 | 3.97 | 3.97 |
| 430.54 | 4.06 | 4.06 |
| 362.51 | 4.62 | 4.62 |
| 448.60 | 4.95 | 4.95 |
| 448.60 | 4.38 | 4.38 |
| 420.55 | 4.82 | 4.82 |
| 406.56 | 4.89 | 4.89 |
| 420.59 | 4.98 | 4.98 |
| 386.53 | 5.23 | 5.23 |
| 302.46 | 3.92 | 3.92 |
| 302.46 | 4.30 | 4.30 |
| 302.46 | 4.30 | 4.30 |
| 316.44 | 4.01 | 4.01 |
| 300.44 | 4.45 | 4.45 |
| 348.48 | 3.97 | 3.97 |
| 334.50 | 3.88 | 3.88 |
| 362.51 | 4.62 | 4.62 |
| 334.46 | 4.49 | 4.49 |
| 334.46 | 4.49 | 4.49 |
| 388.55 | 5.53 | 5.53 |
| 332.44 | 3.50 | 3.50 |
| 316.44 | 4.40 | 4.40 |
| 316.44 | 4.40 | 4.40 |
| 332.44 | 3.50 | 3.50 |
| 314.43 | 4.55 | 4.55 |
| 330.42 | 3.65 | 3.65 |
| 306.49 | 4.47 | 4.47 |
| 290.49 | 5.50 | 5.50 |