Basic Information
ID: ALA1100026
Type: ADME
Description: Inhibition of human recombinant CYP3A4-mediated oxidation of 7-benzyloxyquinoline
Format: BAO_0000357
Organism: Homo sapiens
Target: Cytochrome P450 3A4(ALA340)
Document: ALA1154226
Inhibition of human recombinant CYP3A4-mediated oxidation of 7-benzyloxyquinoline: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1100026
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 720.96 | 5.91 | 5.91 |
| 565.72 | 4.56 | 4.56 |
| 565.72 | 4.56 | 4.56 |
| 565.72 | 4.56 | 4.56 |
| 840.07 | 7.27 | 7.27 |
| 635.86 | 6.32 | 6.32 |
| 635.86 | 6.32 | 6.32 |
| 593.78 | 5.30 | 5.30 |
| 593.78 | 5.30 | 5.30 |
| 593.78 | 5.30 | 5.30 |
| 621.83 | 5.93 | 5.93 |
| 621.83 | 5.93 | 5.93 |
| 621.83 | 5.93 | 5.93 |
| 619.81 | 5.69 | 5.69 |
| 635.86 | 6.32 | 6.32 |
| 655.85 | 6.48 | 6.48 |
| 655.85 | 6.48 | 6.48 |
| 655.85 | 6.48 | 6.48 |
| 685.87 | 6.49 | 6.49 |
| 656.83 | 5.87 | 5.87 |
| 656.83 | 5.87 | 5.87 |
| 645.81 | 5.20 | 5.20 |
| 706.89 | 7.03 | 7.03 |
| 413.53 | 2.07 | 2.07 |
| 441.58 | 2.85 | 2.85 |
| 441.58 | 2.85 | 2.85 |
| 441.58 | 2.85 | 2.85 |
| 525.74 | 4.90 | 4.90 |
| 557.65 | 1.94 | 1.94 |
| 605.87 | 6.75 | 6.75 |
| 653.83 | 5.24 | 5.24 |
| 625.77 | 4.71 | 4.71 |
| 806.02 | 8.45 | 8.45 |
| 561.64 | 4.36 | 4.36 |
| 559.67 | 3.83 | 3.83 |
| 591.80 | 6.51 | 6.51 |
| 581.72 | 5.17 | 5.17 |
| 559.67 | 3.83 | 3.83 |