Basic Information
ID: ALA1100169
Type: Binding
Description: Inhibition of rat recombinant Rab geranylgeranyltransferase at 100 uM in presence of canine Rab7 and rat REP1 NBD-FPP based continuous fluorimetric assay
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA1100169
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 496.61 | 0.84 | 0.84 |
| 544.65 | 2.19 | 2.19 |
| 705.98 | 7.03 | 7.03 |
| 600.76 | 4.01 | 4.01 |
| 567.73 | 3.35 | 3.35 |
| 603.70 | 2.72 | 2.72 |
| 548.55 | 0.13 | 0.13 |
| 539.64 | 0.79 | 0.79 |
| 677.09 | 3.08 | 3.08 |
| 630.70 | 2.10 | 2.10 |
| 664.84 | 3.42 | 3.42 |
| 526.59 | -1.44 | -1.44 |
| 593.73 | 1.02 | 1.02 |
| 562.61 | 1.37 | 1.37 |
| 516.60 | 0.98 | 0.98 |
| 808.99 | 6.27 | 6.27 |
| 835.02 | 6.82 | 6.82 |
| 812.93 | 6.29 | 6.29 |
| 572.62 | 0.86 | 0.86 |
| 584.71 | 1.90 | 1.90 |
| 591.57 | 2.93 | 2.93 |
| 619.63 | 3.56 | 3.56 |
| 617.61 | 3.41 | 3.41 |
| 601.61 | 3.71 | 3.71 |
| 512.58 | 1.06 | 1.06 |
| 527.59 | 1.75 | 1.75 |
| 568.69 | 2.88 | 2.88 |
| 583.70 | 3.57 | 3.57 |
| 612.74 | 3.42 | 3.42 |
| 651.81 | 4.49 | 4.49 |
| 526.59 | -0.25 | -0.25 |
| 587.68 | 1.21 | 1.21 |
| 605.67 | 1.35 | 1.35 |
| 512.56 | -0.34 | -0.34 |
| 601.70 | 0.89 | 0.89 |
| 623.66 | 1.49 | 1.49 |
| 511.58 | -0.94 | -0.94 |
| 617.70 | 1.22 | 1.22 |
| 632.67 | 1.12 | 1.12 |
| 565.54 | 1.94 | 1.94 |
| 607.62 | 2.97 | 2.97 |
| 593.59 | 2.58 | 2.58 |
| 591.58 | 2.43 | 2.43 |
| 551.51 | 1.56 | 1.56 |
| 793.83 | 5.87 | 5.87 |
| 788.93 | 6.12 | 6.12 |
| 614.61 | 2.82 | 2.82 |
| 553.65 | 0.60 | 0.60 |
| 560.09 | 2.14 | 2.14 |
| 567.64 | -0.85 | -0.85 |
| 580.68 | 1.38 | 1.38 |
| 513.57 | 1.66 | 1.66 |
| 605.74 | 1.49 | 1.49 |
| 481.55 | -0.30 | -0.30 |
| 482.54 | 0.30 | 0.30 |
| 496.56 | 0.39 | 0.39 |
| 563.70 | 1.66 | 1.66 |
| 571.68 | 1.53 | 1.53 |
| 530.54 | 1.33 | 1.33 |
| 772.86 | 5.65 | 5.65 |
| 520.51 | 0.06 | 0.06 |
| 1005.15 | ||
| 1005.15 | ||
| 844.97 | 6.83 | 6.83 |
| 546.54 | 1.04 | 1.04 |
| 684.79 | 4.97 | 4.97 |
| 572.57 | 2.02 | 2.02 |
| 844.97 | 6.83 | 6.83 |
| 556.64 | 1.59 | 1.59 |
| 567.64 | 0.06 | 0.06 |
| 606.71 | 1.14 | 1.14 |
| 538.60 | 0.22 | 0.22 |
| 496.57 | -0.80 | -0.80 |
| 557.65 | 1.85 | 1.85 |
| 788.91 | 4.80 | 4.80 |
| 551.64 | 0.07 | 0.07 |
| 593.63 | 2.13 | 2.13 |
| 572.67 | 1.36 | 1.36 |
| 395.42 | -3.32 | -3.32 |
| 546.54 | 1.04 | 1.04 |
| 612.68 | 3.79 | 3.79 |
| 556.58 | 2.32 | 2.32 |
| 651.72 | 4.27 | 4.27 |
| 595.61 | 2.80 | 2.80 |
| 811.90 | 6.13 | 6.13 |
| 569.58 | 1.82 | 1.82 |
| 593.68 | 2.67 | 2.67 |
| 537.57 | 1.20 | 1.20 |
| 633.61 | 1.19 | 1.19 |
| 690.84 | 5.61 | 5.61 |
| 680.63 | 1.44 | 1.44 |
| 841.10 | 8.61 | 8.61 |
| 658.62 | 1.25 | 1.25 |
| 967.23 | 7.96 | 7.96 |
| 523.59 | -0.47 | -0.47 |
| 766.51 | 2.32 | 2.32 |
| 746.88 | 2.01 | 2.01 |
| 756.49 | 1.55 | 1.55 |
| 592.69 | 1.55 | 1.55 |
| 569.67 | 3.48 | 3.48 |
| 652.12 | 2.47 | 2.47 |
| 679.57 | 1.84 | 1.84 |
| 524.57 | 0.13 | 0.13 |
| 470.53 | -0.99 | -0.99 |
| 456.50 | -0.67 | -0.67 |
| 471.51 | -0.61 | -0.61 |
| 582.60 | 1.22 | 1.22 |
| 780.96 | 5.99 | 5.99 |
| 546.62 | 0.94 | 0.94 |
| 345.31 | 0.31 | 0.31 |
| 887.04 | 6.37 | 6.37 |
| 711.86 | 4.51 | 4.51 |
| 737.85 | 3.92 | 3.92 |
| 705.85 | 4.93 | 4.93 |
| 723.82 | 3.83 | 3.83 |
| 665.79 | 4.28 | 4.28 |
| 627.70 | 3.18 | 3.18 |
| 855.99 | 5.21 | 5.21 |
| 667.76 | 4.46 | 4.46 |
| 822.92 | 4.01 | 4.01 |
| 599.64 | 2.49 | 2.49 |
| 613.67 | 2.83 | 2.83 |
| 705.77 | 4.07 | 4.07 |
| 705.77 | 4.07 | 4.07 |
| 843.06 | 7.60 | 7.60 |
| 639.71 | 3.82 | 3.82 |
| 609.68 | 3.77 | 3.77 |
| 641.68 | 3.18 | 3.18 |
| 641.68 | 3.18 | 3.18 |
| 693.84 | 5.03 | 5.03 |
| 644.64 | 2.40 | 2.40 |
| 705.77 | 4.07 | 4.07 |
| 673.77 | 3.98 | 3.98 |
| 663.77 | 4.21 | 4.21 |
| 667.81 | 4.05 | 4.05 |
| 665.79 | 4.13 | 4.13 |
| 667.81 | 4.05 | 4.05 |
| 576.63 | 0.84 | 0.84 |
| 598.58 | 1.44 | 1.44 |
| 758.39 | 2.62 | 2.62 |
| 762.83 | 4.37 | 4.37 |
| 587.07 | 0.83 | 0.83 |
| 524.62 | 1.16 | 1.16 |
| 564.68 | 2.11 | 2.11 |
| 560.65 | 0.62 | 0.62 |
| 552.67 | 0.75 | 0.75 |
| 538.65 | 0.31 | 0.31 |
| 623.79 | 3.15 | 3.15 |
| 631.73 | 0.78 | 0.78 |
| 539.63 | 0.62 | 0.62 |
| 578.70 | 1.70 | 1.70 |
| 839.38 | 3.03 | 3.03 |
| 727.45 | 1.25 | 1.25 |
| 552.67 | 1.94 | 1.94 |
| 577.73 | 2.05 | 2.05 |
| 540.62 | -0.84 | -0.84 |
| 487.48 | -0.39 | -0.39 |
| 647.29 | 0.79 | 0.79 |
| 728.36 | 4.00 | 4.00 |
| 615.03 | 1.95 | 1.95 |
| 722.41 | 2.35 | 2.35 |
| 727.91 | 3.61 | 3.61 |
| 847.07 | 6.22 | 6.22 |
| 706.88 | 2.60 | 2.60 |
| 676.86 | 4.15 | 4.15 |
| 632.81 | 3.61 | 3.61 |
| 647.82 | 4.30 | 4.30 |
| 676.86 | 3.63 | 3.63 |
| 723.92 | 5.35 | 5.35 |
| 633.79 | 4.21 | 4.21 |
| 648.80 | 3.63 | 3.63 |
| 704.91 | 4.97 | 4.97 |
| 713.88 | 3.56 | 3.56 |
| 699.86 | 3.89 | 3.89 |
| 546.61 | 1.80 | 1.80 |
| 555.68 | 3.77 | 3.77 |
| 595.70 | 2.67 | 2.67 |
| 496.56 | 0.69 | 0.69 |
| 586.78 | 4.40 | 4.40 |
| 538.62 | 2.34 | 2.34 |
| 540.62 | 0.31 | 0.31 |
| 652.55 | 3.00 | 3.00 |
| 562.60 | 1.16 | 1.16 |
| 556.59 | -0.62 | -0.62 |
| 647.70 | 1.00 | 1.00 |
| 807.51 | 2.18 | 2.18 |
| 549.98 | 0.30 | 0.30 |
| 580.67 | 1.18 | 1.18 |
| 485.54 | -0.53 | -0.53 |
| 568.65 | 0.97 | 0.97 |
| 858.05 | 7.54 | 7.54 |
| 569.70 | 3.86 | 3.86 |
| 574.63 | 3.13 | 3.13 |
| 513.55 | 0.86 | 0.86 |
| 499.52 | 0.77 | 0.77 |
| 542.59 | 0.71 | 0.71 |
| 498.54 | 0.17 | 0.17 |
| 709.79 | 1.49 | 1.49 |
| 661.32 | 0.88 | 0.88 |
| 501.51 | -0.31 | -0.31 |
| 639.76 | 3.37 | 3.37 |
| 844.45 | 7.29 | 7.29 |
| 450.49 | -2.45 | -2.45 |
| 568.67 | 0.92 | 0.92 |
| 495.58 | 0.09 | 0.09 |
| 606.07 | 3.06 | 3.06 |
| 612.66 | 2.74 | 2.74 |
| 592.67 | 1.68 | 1.68 |
| 825.02 | 6.01 | 6.01 |
| 551.66 | 1.98 | 1.98 |
| 648.81 | 3.32 | 3.32 |
| 692.86 | 3.34 | 3.34 |
| 703.85 | 3.65 | 3.65 |
| 717.87 | 3.73 | 3.73 |
| 702.86 | 3.05 | 3.05 |
| 744.94 | 3.64 | 3.64 |
| 753.95 | 5.45 | 5.45 |
| 591.65 | 1.89 | 1.89 |
| 634.78 | -0.24 | -0.24 |
| 513.55 | -0.32 | -0.32 |
| 571.63 | 1.00 | 1.00 |
| 611.74 | 2.82 | 2.82 |
| 566.66 | 1.60 | 1.60 |
| 626.09 | 2.52 | 2.52 |
| 588.67 | 1.23 | 1.23 |
| 380.40 | -2.83 | -2.83 |
| 855.04 | 4.98 | 4.98 |
| 541.51 | 1.65 | 1.65 |
| 676.69 | 3.34 | 3.34 |
| 662.67 | 3.66 | 3.66 |
| 640.71 | 3.06 | 3.06 |
| 607.68 | 3.08 | 3.08 |
| 632.73 | 3.19 | 3.19 |
| 551.57 | 1.83 | 1.83 |
| 644.68 | 3.52 | 3.52 |
| 594.64 | 1.76 | 1.76 |
| 704.88 | 5.39 | 5.39 |
| 523.52 | 1.51 | 1.51 |
| 537.57 | 1.36 | 1.36 |
| 522.56 | 0.67 | 0.67 |
| 630.71 | 1.59 | 1.59 |
| 662.83 | 4.02 | 4.02 |
| 665.84 | 1.99 | 1.99 |
| 810.05 | 5.68 | 5.68 |
| 586.69 | 1.75 | 1.75 |
| 605.69 | 3.67 | 3.67 |
| 686.85 | 5.04 | 5.04 |
| 821.08 | 7.27 | 7.27 |
| 651.81 | 2.51 | 2.51 |
| 900.13 | 7.61 | 7.61 |
| 858.10 | 6.92 | 6.92 |
| 755.96 | 4.34 | 4.34 |
| 627.70 | 1.89 | 1.89 |
| 641.73 | 2.28 | 2.28 |
| 449.51 | 1.62 | 1.62 |
| 463.53 | 1.71 | 1.71 |
| 653.53 | 1.88 | 1.88 |
| 478.52 | 0.71 | 0.71 |
| 516.60 | -0.67 | -0.67 |
| 609.70 | 0.62 | 0.62 |
| 502.57 | -0.75 | -0.75 |
| 613.67 | 1.08 | 1.08 |
| 583.73 | 0.61 | 0.61 |
| 537.54 | 1.59 | 1.59 |
| 579.63 | 2.77 | 2.77 |
| 598.63 | 3.06 | 3.06 |
| 634.61 | 3.34 | 3.34 |
| 604.68 | 2.87 | 2.87 |
| 746.96 | 7.02 | 7.02 |
| 566.59 | 1.44 | 1.44 |
| 593.66 | 1.28 | 1.28 |
| 614.07 | 2.52 | 2.52 |
| 565.60 | 1.91 | 1.91 |
| 626.69 | 3.38 | 3.38 |
| 530.67 | 2.98 | 2.98 |
| 518.66 | 2.70 | 2.70 |
| 506.56 | 1.42 | 1.42 |
| 666.77 | 5.60 | 5.60 |
| 492.55 | 0.80 | 0.80 |
| 635.54 | 2.34 | 2.34 |
| 570.67 | 1.69 | 1.69 |
| 586.02 | 2.20 | 2.20 |
| 755.78 | 3.71 | 3.71 |
| 661.66 | 3.05 | 3.05 |
| 758.73 | 4.79 | 4.79 |
| 728.79 | 4.33 | 4.33 |
| 736.77 | 4.19 | 4.19 |
| 710.13 | 3.66 | 3.66 |
| 729.76 | 3.97 | 3.97 |
| 717.77 | 2.73 | 2.73 |
| 690.70 | 2.38 | 2.38 |
| 647.63 | 2.96 | 2.96 |
| 745.96 | 6.85 | 6.85 |
| 759.98 | 6.94 | 6.94 |
| 828.09 | 7.86 | 7.86 |
| 857.05 | 8.68 | 8.68 |
| 878.12 | 7.46 | 7.46 |
| 760.97 | 6.01 | 6.01 |
| 799.07 | 7.44 | 7.44 |
| 816.10 | 6.62 | 6.62 |
| 787.01 | 5.85 | 5.85 |
| 808.46 | 7.55 | 7.55 |
| 871.08 | 8.36 | 8.36 |
| 853.12 | 7.17 | 7.17 |
| 789.03 | 6.27 | 6.27 |
| 592.62 | 1.28 | 1.28 |
| 781.95 | 6.59 | 6.59 |
| 795.97 | 6.68 | 6.68 |
| 825.02 | 6.53 | 6.53 |
| 863.11 | 7.96 | 7.96 |
| 907.07 | 8.10 | 8.10 |
| 893.04 | 8.43 | 8.43 |
| 889.11 | 6.91 | 6.91 |
| 755.91 | 5.61 | 5.61 |
| 637.78 | 3.02 | 3.02 |
| 776.94 | 2.03 | 2.03 |
| 623.76 | 2.94 | 2.94 |
| 746.91 | 3.06 | 3.06 |
| 822.05 | 6.92 | 6.92 |
| 782.98 | 5.84 | 5.84 |
| 782.98 | 5.32 | 5.32 |
| 738.93 | 5.31 | 5.31 |
| 739.91 | 5.91 | 5.91 |
| 813.01 | 4.29 | 4.29 |
| 809.02 | 5.68 | 5.68 |
| 652.80 | 1.96 | 1.96 |
| 696.85 | 1.32 | 1.32 |
| 666.82 | 2.35 | 2.35 |
| 649.79 | 3.92 | 3.92 |
| 756.95 | 4.24 | 4.24 |
| 696.85 | 1.32 | 1.32 |
| 740.95 | 4.53 | 4.53 |
| 637.78 | 3.02 | 3.02 |
| 693.89 | 2.71 | 2.71 |
| 730.91 | 3.25 | 3.25 |
| 713.88 | 4.07 | 4.07 |
| 665.84 | 3.96 | 3.96 |
| 622.77 | 2.34 | 2.34 |
| 623.76 | 2.94 | 2.94 |
| 699.86 | 3.89 | 3.89 |
| 713.88 | 3.98 | 3.98 |
| 752.92 | 5.10 | 5.10 |
| 639.75 | 2.28 | 2.28 |
| 682.82 | 1.70 | 1.70 |
| 746.91 | 2.60 | 2.60 |
| 561.68 | 1.07 | 1.07 |
| 617.80 | 0.75 | 0.75 |
| 623.76 | 1.93 | 1.93 |
| 501.58 | 2.10 | 2.10 |
| 636.84 | 5.13 | 5.13 |
| 630.74 | 4.54 | 4.54 |
| 710.23 | 5.89 | 5.89 |
| 624.83 | 4.85 | 4.85 |
| 607.75 | 4.25 | 4.25 |
| 724.70 | 6.19 | 6.19 |
| 574.77 | 4.11 | 4.11 |
| 557.69 | 3.52 | 3.52 |
| 505.62 | 3.03 | 3.03 |
| 519.64 | 3.12 | 3.12 |
| 538.65 | 2.47 | 2.47 |
| 552.67 | 2.56 | 2.56 |
| 537.66 | 1.87 | 1.87 |
| 693.64 | 4.19 | 4.19 |
| 581.71 | 2.41 | 2.41 |
| 610.71 | 1.78 | 1.78 |
| 607.75 | 2.25 | 2.25 |
| 663.84 | 3.94 | 3.94 |
| 605.78 | 3.40 | 3.40 |
| 601.14 | 3.17 | 3.17 |
| 546.67 | 0.38 | 0.38 |
| 552.59 | 0.30 | 0.30 |
| 509.52 | 0.88 | 0.88 |
| 457.46 | 0.98 | 0.98 |
| 478.52 | -0.64 | -0.64 |
| 549.64 | 1.76 | 1.76 |
| 471.49 | 1.07 | 1.07 |
| 552.68 | 1.38 | 1.38 |
| 562.58 | 0.22 | 0.22 |
| 538.65 | 0.19 | 0.19 |
| 523.55 | 0.97 | 0.97 |
| 508.54 | 0.28 | 0.28 |
| 582.61 | -0.73 | -0.73 |
| 609.64 | 2.56 | 2.56 |
| 616.68 | 1.20 | 1.20 |
| 566.62 | 0.69 | 0.69 |
| 596.64 | -0.34 | -0.34 |
| 613.68 | 2.41 | 2.41 |
| 411.39 | -1.92 | -1.92 |
| 572.79 | 6.29 | 6.29 |
| 466.51 | -0.93 | -0.93 |
| 615.77 | 4.70 | 4.70 |
| 664.24 | 5.31 | 5.31 |
| 616.20 | 3.96 | 3.96 |
| 553.70 | 3.26 | 3.26 |
| 601.74 | 4.61 | 4.61 |
| 552.72 | 2.66 | 2.66 |
| 562.58 | -0.96 | -0.96 |
| 549.54 | 0.73 | 0.73 |
| 621.60 | 0.04 | 0.04 |
| 509.65 | 0.40 | 0.40 |
| 523.55 | 1.27 | 1.27 |
| 605.68 | 2.28 | 2.28 |
| 664.80 | 3.34 | 3.34 |
| 720.91 | 4.68 | 4.68 |
| 638.77 | 2.36 | 2.36 |
| 694.88 | 3.70 | 3.70 |
| 562.67 | 0.40 | 0.40 |
| 618.78 | 1.74 | 1.74 |
| 480.48 | 0.36 | 0.36 |
| 559.66 | 2.88 | 2.88 |
| 497.59 | 1.44 | 1.44 |
| 511.62 | 1.53 | 1.53 |
| 608.14 | 3.48 | 3.48 |
| 495.62 | 0.31 | 0.31 |
| 532.08 | 0.31 | 0.31 |
| 553.66 | 0.87 | 0.87 |
| 494.50 | 0.45 | 0.45 |
| 496.52 | -0.67 | -0.67 |
| 496.52 | -0.67 | -0.67 |
| 520.54 | 1.01 | 1.01 |
| 632.76 | 4.13 | 4.13 |
| 623.17 | 2.66 | 2.66 |
| 494.64 | -0.29 | -0.29 |