Assay Report Card

Basic Information

ID: ALA1100176

Type: Binding

Description: Inhibition of recombinant Rab geranylgeranyltransferase expressed in human MCF7 cells assessed as inhibition of geranylgeranylation of EYFP-Rab7 protein at 100 uM to 0.5 mM by Western blot relative to compactin

Cell type: MCF7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
247.14-0.43-0.43
651.723.033.03
628.692.262.26
762.834.374.37
741.943.953.95
767.974.934.93
751.975.225.22