Basic Information
ID: ALA1101142
Type: Binding
Description: Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrs
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA1101142
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 408.88 | 1.84 | 1.84 |
| 394.85 | 1.45 | 1.45 |
| 372.46 | 1.66 | 1.66 |
| 402.49 | 1.46 | 1.46 |
| 356.46 | 2.69 | 2.69 |
| 408.88 | 2.11 | 2.11 |
| 356.46 | 2.69 | 2.69 |
| 372.46 | 1.66 | 1.66 |
| 378.85 | 2.48 | 2.48 |
| 372.46 | 1.66 | 1.66 |
| 408.88 | 2.11 | 2.11 |
| 378.85 | 2.48 | 2.48 |
| 410.87 | 3.09 | 3.09 |
| 424.88 | 0.82 | 0.82 |
| 398.50 | 2.81 | 2.81 |
| 368.47 | 2.83 | 2.83 |
| 370.45 | 2.28 | 2.28 |
| 383.49 | 1.64 | 1.64 |
| 432.54 | 1.47 | 1.47 |
| 384.47 | 2.07 | 2.07 |
| 386.44 | 1.52 | 1.52 |
| 406.86 | 1.86 | 1.86 |
| 420.89 | 2.25 | 2.25 |